LI Li, XIAO Yong-qing, LIU Ying, et al. Main Substance and Biological Activity of Acidic Components of [J]. Chinese journal of experimental traditional medical formulae, 2014, 20(6): 70-73.
DOI:
LI Li, XIAO Yong-qing, LIU Ying, et al. Main Substance and Biological Activity of Acidic Components of [J]. Chinese journal of experimental traditional medical formulae, 2014, 20(6): 70-73. DOI: 10.11653/syfj2014050070.
Main Substance and Biological Activity of Acidic Components of
Objective: Reveal the composition of acidic components and its biological activity of Schisandra chinensis. Method: Using organic solvent extraction
macroporous resin separation and solvent treatment to prepare acidic components from S. chinensis
HPLC were applied for qualitative and quantitative analysis. Meanwhile
the influence of acidic components in swimming time
resistance to atmospheric oxygen
weight of immune organs and influence of immune phagocytosis in mice were observed. Result: The acidic components were mainly consisted of citric acid
quinic acid and other organic acids
the total amount of two acids were reached 55.8%. Low dose (5 g·kg-1)sour substance could significantly prolong the swimming time of mice (P<0.001) and the thymus index
spleen index compared with the control group enhance significantly in mice (P<0.05
P<0.01); high and low dose sour substance can be notably increase the mouse peritoneal macrophage phagocytic function to improve the phagocytic index and phagocytic coefficient K value of a value; especially
there was a significant difference between the low dose group and normal control group (P<0.001
P<0.01). Conclusion: Acidic componnets of S.e chinensis with anti-fatigue and immune enhancement effect better
is an important component of S. chinensis pharmacodynamic material bases.
Effect of Polysaccharides from Root, Stem, Leaf and Fruit of Schisandra chinensis on Exercise Endurance in D-galactose-induced Aging Mice
Changes in Effective Compounds and Anti-fatigue Activity Before and After Compatibility of Ginseng Radix et Rhizoma Rubra and Rhodiolae Crenulate Radix et Rhizoma
Promotive Effect of Jufeng Ⅰ,Ⅱ Oral Liquids on the Sport Activity in Mice
Experimental studies on anti-fatigue of Campou Medicine Qi-Xue-Shuei prescription No1
Determination of Optimum Dosage of Ingredieunts in XingShenFang by Uniform-design Method
Related Author
Jia-hui FANG
Jia-wei LIU
Yu-xin JIANG
Shu JING
Chun-mei WANG
Jing-hui SUN
Cheng-yi ZHANG
Jian-guang CHEN
Related Institution
College of Pharmacy, Beihua University
Affiliated Hospital of Beihua University
Jilin Ginseng Academy,Changchun University of Chinese Medicine
The Third Clinical Medical Hospital of Changchun University of Chinese Medicine