HU Yan, LUO Bin, LI Yun-long. Optimization of A Novel Formulation for Cataplasms Matrix Materials[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(6): 33-35.
DOI:
HU Yan, LUO Bin, LI Yun-long. Optimization of A Novel Formulation for Cataplasms Matrix Materials[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(6): 33-35. DOI: 10.11653/syfj2014060033.
Optimization of A Novel Formulation for Cataplasms Matrix Materials
Objective: Based on traditional cataplasmsmatrix materials
to optimize a novel formulation of cataplasms matrix materials. Method: With initial adhesion
peeling strength
phosphorus and sensory evaluation as comprehensive evaluation index
orthogonal test was adopted to optimize cataplasmsmatrix formulation by taking sodium polyacrylate
gelatin and sodium hyaluronate as adhesives
glycerol
propylene glycol and polyethylene glycol as moisturizers
attapulgite clay and zinc oxide as fillers
aluminum chloride as crosslinking agent. Result: Optimum matrix formulation was sodium polyacrylate-gelatin-sodium hyaluronate-glycerol-propylene glycol-polyethyleneglycol-AlCl3(4.5:2.5:2.0:13:13:13:0.2). Conclusion: These prepared cataplasmshad a certain application value with good initial adhesion
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Related Author
ZHU Yin-long
CHEN Ping
ZHANG Ya-huan
CUI Han-ming
XIA Pi-fang
CHENG Hui-ping
ZHANG Chao1
LV Hua-ying2
Related Institution
Key Laboratory of New Drug Delivery System of Chinese Meteria Medica,Jiangsu Provincial Academy of Chinese Medicine, Key Laboratory of Scientific Preparation for Clinical Effective Prescription of State Administration of Traditional Chinese Medicine
Drug Research Center for Nephropathy,Guangzhou Consun Pharmaceutical Co.Ltd
Hunan University of Chinese Medicine
Hunan Academy of Chinese Medicine
Hunan Key Laboratory of Chinese Medicine Powder and Innovation Drug Province Department Co-construction