Objective: To discuss the influence of ischemic stroke traditional Chinese medicine syndrome types differentiated from yin-syndrome and yang-syndrome and its efficacy system on treating symptomatic middle cerebral artery atherosclerosis stenosis on prognosis. Method: Forty-six patients of symptomatic middle cerebral artery atherosclerosis stenosis treated with ischemic stroke traditional Chinese medicine syndrome types differentiated from yin-syndrome and yang-syndrome and its efficacy system with medical treatment(observation group) and thirty-five patients of the same disease with only medical treatment (control group) were retrospectively analyzed. the rates of recurrent stroke and mortality of the two groups in the follow-ups were recorded. The haemodynamics results were evaluated by TCD(transcranial dopper) and mRS(modified rankin scale) were evaluated. Result: In the average periods of follow-ups

the rates of recurrent stroke were 6.52% in the observation group and 22.86% in the control group(P<0.05);the mortality rates were 4.35% in the observation group and 14.29% in the control group

which were statistically insignificant. The ratio of Vs(peak value of systole) before and after treatment was statistically significant (P<0.05) in the observation group

while the ratio in the control group was statistically insignificant. After the treatment

the ratio compared with the two groups were statistically significant (P<0.05). Conclusion: Ischemic stroke traditional Chinese medicine syndrome types differentiated from yin-syndrome and yang-syndrome and its efficacy system with medical treatment is proved to reduce the rate of recurrent ischemic stroke

change the brain blood speed and improve the neurological defects with regard to the patients suffered from symptomatic middle cerebral artery atherosclerosis stenosis.