WEN Ran, GAO Ying, LU Yang, et al. Optimization of Extraction Technology for Guyu Liniment by Orthogonal Design[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(7): 39-41.
DOI:
WEN Ran, GAO Ying, LU Yang, et al. Optimization of Extraction Technology for Guyu Liniment by Orthogonal Design[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(7): 39-41. DOI: 10.11653/zgsyfjxzz2013070039.
Optimization of Extraction Technology for Guyu Liniment by Orthogonal Design
Objective: To optimize extraction process of Guyu liniment. Method: Orthogonal test was employed to optimize extraction procedure
including the concentration of ethanol
the amount of solvent
extraction time and extracting times.The content of hydroxy safflor yellow A(HSYA) was used as index which was determined by HPLC. Result: Optimum extracting process for Guyu liniment was as follows:reflux extracted 2 times with 12 times the amount of 70% ethanol
1.5 h per time. Conclusion: This optimized process was stable and feasible with relatively high content of HSYA.
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Related Author
TAN Li-rong
LIANG Hai-chun
WU Dian-wei
SU Ji-yan
LIU Wei-jin
SU Zi-ren
TAN Li-rong1
LIANG Hai-chun1
Related Institution
Dongguan Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine
New Drug Research and Development Center,Guangzhou University of Chinese Medicine
Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences
上海中医药大学中药现代制剂技术教育部工程研究中心
Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine