HU Hai-yan, PENG Cheng. Influences of Compatibility of Emodin and Aconitine on the Biomembrane of the Interstitial Cells of Cajal[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(7): 189-192.
DOI:
HU Hai-yan, PENG Cheng. Influences of Compatibility of Emodin and Aconitine on the Biomembrane of the Interstitial Cells of Cajal[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(7): 189-192. DOI: 10.11653/zgsyfjxzz2013070189.
Influences of Compatibility of Emodin and Aconitine on the Biomembrane of the Interstitial Cells of Cajal
Objective: To investigate influences of compatibility of emodin and aconitine on the biomembrane of in vitro cultured interstitial cells of Cajal(ICC) from murine conlon. Method: ICCs of kunming mice's conlon were obtained by enzyme-digestion and culture in vitro. ICCs were cultured with compatibility of emodin(1
0.3
0.08 mg·L-1) and aconitine(1 g·L-1) to study the changes of malondialdehyde(MDA) and acid phosphatase(ACP). Result: Aconitine could increase the content of MDA and the activity of ACP in the cells(P<0.01). The compatibility of emodin and aconitine could reduce the content of MDA and the activity of ACP in the cells(P<0.05). Conclusion: Emodin can lighten the cell trauma of lysosomal membrane witch caused by aconitine.The compatibility of emodin and aconitine can protect the cell biomembrane.
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