XU Fei-fei, PENG Cheng, WANG Zhuo-kang, et al. Effects of the Shenfu Injection on ATPase and Related Ion of Heart Failure Model Myocardial Cell[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(7): 196-199.
DOI:
XU Fei-fei, PENG Cheng, WANG Zhuo-kang, et al. Effects of the Shenfu Injection on ATPase and Related Ion of Heart Failure Model Myocardial Cell[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(7): 196-199. DOI: 10.11653/zgsyfjxzz2013070196.
Effects of the Shenfu Injection on ATPase and Related Ion of Heart Failure Model Myocardial Cell
Objective: To study the effects of Shenfu injection on the Ca2+-Mg2+-ATP ase
Ca2+-ATP ase
Na+-K+-ATP and Na+
Mg2+
K+
Ca2+ in the myocardial cell injured by nembutal. Method: The myocardial cell is gotten by trypsin digestion and purified by different velocity of adherence. After injured by 0.8% nembutal
the myocardial cell is administrated with 3 different concentrations of Shenfu Injection. Then mensurate the vitality of the Ca2+-Mg2+-ATP ase
Na+-K+-ATP ase and Ca2+-ATP ase and Na+
Mg2+
K+
Ca2+ in the cell 1 h later. Result: The Shenfu injection can increase the strength of the myocardial cell beating injured by nembutal
and enhance the activity of Ca2+-ATP ase and the Ca2+-Mg2+-ATP ase
inhibit the the activity of Na+-K+-ATP
enzyme increase the content of Na+
Mg2+ and decrease the content of K+
Ca2+ in the myocardial cell. Conclusion: The Shenfu injection can protect the myocardial cell injured by nembutal
and the function is relevent to the effects of Shenfu injection on the Ca2+-Mg2+-ATP ase
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