CHEN Guo-hua, PAN Guang-hui, SHEN Shou-xiang, et al. Influence of Zhengan Xifeng Granule on Insulin Sensitivity in Hypertension[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(7): 293-296.
DOI:
CHEN Guo-hua, PAN Guang-hui, SHEN Shou-xiang, et al. Influence of Zhengan Xifeng Granule on Insulin Sensitivity in Hypertension[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(7): 293-296. DOI: 10.11653/zgsyfjxzz2013070293.
Influence of Zhengan Xifeng Granule on Insulin Sensitivity in Hypertension
Objective: To observe the effects of Zhengan Xifeng granule on insulin sensitivity
blood pressure
blood glucose and blood lipid in hypertension patients. Method: Sixty-six hyper-tension patients with insulin resistance were randomly divided into treatment group (cooperation of chinese and western medicine group) and control group(western medicine group). Each group was treated for 6 months and then the blood pressure (BP)
fasting blood glucose (FBG)
total cholesterol (TC)
the triglyceride (TG)
low-or high-density lipoprotein-cholesterol (LDL-C or HDL-C)
free fatty acids
as well as insulin sensitivity index (ISI) were measured. Result: Compared to the control group
the contents of the treatment group were significantly improved as follow:BP decreased(P<0.01)
FBG
TC
TG
LDL-C and FFA lowered
HDL-C increased(P<0.05) and the ISl weakened(P<0.05). Conclusion: Zhengan Xifeng granule appeared to decrease blood pressure
stable the blood glucose and blood fat
suppress insulin resistance
enhance the insulin sensitivity as well as modify hyperinsulinemia.