ZHOU Jing-rong. Clinical Observation on Tianma Gouteng Granules Combined with Western Medicine for Treatment of Senile Hypertension[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(7): 327-330.
DOI:
ZHOU Jing-rong. Clinical Observation on Tianma Gouteng Granules Combined with Western Medicine for Treatment of Senile Hypertension[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(7): 327-330. DOI: 10.11653/zgsyfjxzz2013070327.
Clinical Observation on Tianma Gouteng Granules Combined with Western Medicine for Treatment of Senile Hypertension
Objective: To study the clinical curative effect of Tianma Gouteng granules (TGG) combined with nifedipine controlled release tablets and captopril for treatment of senile hypertension with hyperactivity of Yang due to deficiency of Yin. Method: Ninety-seven cases of primary hypertension were randomly divided into the treatment group and the control group
48 cases and 49 cases respectively. Control group was given nifedipine controlled release tablets
30 mg daily
captopril
12.5 mg tid orally. The treatment group was received TGG 10 g tid orally plus the western medicines as in the controls.The interventions in two groups were lasted for 12 weeks. Blood pressure controlling rate
changes in urine albumin creatinine ratio (UACR) and Chinese clinical syndromes were investigated. Result: In treatment group
systolic blood pressure (SBP) level was lower than that in control group (P<0.01). The controlling rate for SBP and diastolic blood pressure (DBP) in treatment group was 72.91% (35/48)
while 59.18% (29/49) in the control group. The UACR level in treatment group was lower than that in control group (P<0.01). The score of hyperactivity of Yang due to deficiency of Yin in the treatment group was lower than that in the control group. The curative effect of TGG for the score of Chinese medical syndrome was better than that in the control group (P<0.01). Conclusion: TGG combined with captopril and nifedipine controlled release tablets for treatment of senile hypertension with hyperactivity of Yang due to deficiency of Yin
shows high success rate for blood pressure controlling
improvement of clinical symptoms
and certain protection effect on early renal damage induced by hypertension. TGG is worth for spreading use in clinic.
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Related Author
WU Jibiao
LI Xiao
TIAN Zifang
WANG Sutong
WANG Lin
CHEN Changjing
XU Xiangdong
ZHANG Yimei
Related Institution
Shandong University of Traditional Chinese Medicine(TCM)
Affiliated Hospital of Shandong University of TCM
The Second Affiliated Hospital of Shandong University of TCM