Clinical Effects of Adjuvant Therapy on Elderly Chronic Heart Failure Patients with Traditional Mongolian Medicine

LIU Sa-ren; TONG Yu-qing; JIN Tao; ZHANG Qing-shan; BAO Burenbaiyila

doi:10.13422/j.cnki.syfix.2014070208

您当前的位置：

首页 >

文章列表页 >

Clinical Effects of Adjuvant Therapy on Elderly Chronic Heart Failure Patients with Traditional Mongolian Medicine

更新时间：2024-01-04

- Clinical Effects of Adjuvant Therapy on Elderly Chronic Heart Failure Patients with Traditional Mongolian Medicine
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 20, Issue 7, Pages: 208-211(2014)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfix.2014070208
  CLC：
- Published：2014
- 稿件说明：
移动端阅览
LIU Sa-ren, TONG Yu-qing, JIN Tao, et al. Clinical Effects of Adjuvant Therapy on Elderly Chronic Heart Failure Patients with Traditional Mongolian Medicine[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(7): 208-211.
DOI：

LIU Sa-ren, TONG Yu-qing, JIN Tao, et al. Clinical Effects of Adjuvant Therapy on Elderly Chronic Heart Failure Patients with Traditional Mongolian Medicine[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(7): 208-211. DOI： 10.13422/j.cnki.syfix.2014070208.

摘要

目的：探讨蒙药治疗老年慢性心力衰竭（CHF）患者的临床疗效及对患者血液流变学、血浆D-二聚体的影响。方法：将108例老年CHF患者随机按入院前后分成对照组和观察组各54例。对照组采用西药强心、利尿、扩血管等常规治疗；观察组在对照组治疗的基础上加用蒙药治疗，达力-16味散每次5 g早饭后口服，蒺藜-3味汤每次5 g午饭后口服，绍沙-7味丸每次3 g晚睡前口服。两组疗程均为12周。进行治疗前后纽约心脏病协会（NYHA）心功能分级和Lee氏心衰计分；采用超声心动图测定治疗前后心室射血分数（LVEF）、左室舒张末期内径（LVDD）和心输出量（CO）；进行治疗前后血液流变学、血浆D-二聚体和血浆N端脑钠肽前体（NT-proBNP）检测。结果：治疗后观察组总有效率为87.04%优于对照组的70.37%（P<0.05）；治疗后观察组Lee氏心衰积分低于对照组（P<0.01）；治疗后观察组LVDD低于对照组（P<0.05）；观察组LVEF和CO高于对照组（P<0.01）；治疗后观察组NT-proBNP，D-二聚体水平低于对照组（P<0.01）；治疗后观察组全血黏度、红细胞变形指数、纤维蛋白原的改善优于对照组（P<0.05）。结论：在西医常规治疗的基础上给予老年CHF患者达力-16味散、蒺藜-3味汤和绍沙-7味丸3种蒙药治疗，能改善老年CHF患者心功能，减轻临床症状，提高临床疗效；还能改善患者血液流变学及血液高凝状态，值得临床使用。

Abstract

Objective: The purpose is to discuss the clinical effects of traditional Mongolian medicine to treat chronic cardiac failure(CHF) and influence of hemorheology

plasma D-dimer on patients. Method: One hundred and eight cases of patients with were randomly divided into control group (54 cases) and observation group (54 cases).In control group

patients were treated with western medicine conventional therapy by cardiac

diuresis

vascular dilation and so on. In observation group

besides based on control group

patients added traditional Mongolian medicine

Dali-16 wei san 5 g

taken orally after breakfast;Jili-3 wei decoction 5 g

taken orally after lunch;Shaosha-7wei pill 3 g

taken orally before sleep.Both groups were treated for 12 weeks.Record New york heart association(NYHA) cardiac functional grading and Lee's heart failure scores before and after treatment.Measure the left ventricular ejection fraction (LVEF)

left ventricular end diastolic diameter(LVDD) and cardiac output(CO) by ultrasonic cardiogram at pretherapy and post-treatment.Detect hemorheology

plasma D-dimer and N-terminal plasma brain natriuretic peptide precursor (NT-proBNP)before and after treatment. Result: After treatment

the total effective rate of the observation group was 87.4% superior to 70.37% of the control group(P<0.05). the Lee's heart failure scores of the observation group were lower than the control group(P<0.01)

Left ventricular end diastolic dimension(LDVV) of the observation group was lower than the control group(P<0.05)

LVEF and CO of the observation group were higher than the the control group(P<0.01). The level of NT-proBNP and D-dimer of the observation group were lower than the control group(P<0.01). The improvement of blood viscosity

erythrocyte deformation index(RCD) and fibrinogen of the observation group were superior to the control group(P<0.05). Conclusion: Based on the routine western medicine therapy

for the elderly patients

it can improve the cardiac function

relief clinical symptom and improve clinical effects when Dali-16 wei san

Jili-3 wei decoction and Shaosha-7 wei pill of the three traditional Mongolian medicine were used in CHF.Besides

it can also improve the hemorheology and hypercoagulable state

worthy of clinical using.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Effect of Maxing Wuzi Decoction in Treating 55 Cases with Acute Exacerbations of Phlegm-damp Obstructing Lung Type Pulmonary Heart Disease

Effect of Qishao Huoxue Prescription on Hemorheological Parameters and Serum Levels of Inflammatory Mediators in Lumbar Disc Herniation Due to Qi Stagnation and Blood Stasis

Application of Insect Medicines in Treatment of Coronary Microvascular Dysfunction Based on Comorbidity Theory of "Blood-Vessel-Cardiac Collaterals"

Protection Mechanism of Addition and Subtraction Therapy of Danshenyin Combined with Wendantang for Myocardial Ischemia in Patients with Stable Angina

Effect of Erxian Decoction on Myocardial Microvessels and Hemorheology in Ovariectomized Rats

Related Author

WU Jian-shun

CAO De-sheng

LI Qiang

LI Hui

WANG Guojun

ZHANG Shimin

JIN Jiao

LIU Ning

Related Institution

Wangjing Hospital of China Academy of Chinese Medical Sciences

Guang'anmen Hospital， China Academy of Chinese Medical Sciences

Hainan Hospital of Traditional Chinese Medicine

Haikou Affiliated Hospital of Central South University Xiangya School of Mcdicine

Institute of Basic Theory of Chinese Medicine，China Academy of Chinese Medical Sciences

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰