Tongluo Zhitong Decoction Combined with Tapping and Cupping Treatment in 60 Cases of Senile Postherpetic Neuralgia

WANG Xiao-li; ZHANG Yue-ying; QIU Shu-guang; LIU Xue-wei

doi:10.13422/j.cnki.syfix.2014070212

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Tongluo Zhitong Decoction Combined with Tapping and Cupping Treatment in 60 Cases of Senile Postherpetic Neuralgia

更新时间：2024-01-04

- Tongluo Zhitong Decoction Combined with Tapping and Cupping Treatment in 60 Cases of Senile Postherpetic Neuralgia
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 20, Issue 7, Pages: 212-215(2014)
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- DOI：10.13422/j.cnki.syfix.2014070212
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- Published：2014
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WANG Xiao-li, ZHANG Yue-ying, QIU Shu-guang, et al. Tongluo Zhitong Decoction Combined with Tapping and Cupping Treatment in 60 Cases of Senile Postherpetic Neuralgia[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(7): 212-215.
DOI：

WANG Xiao-li, ZHANG Yue-ying, QIU Shu-guang, et al. Tongluo Zhitong Decoction Combined with Tapping and Cupping Treatment in 60 Cases of Senile Postherpetic Neuralgia[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(7): 212-215. DOI： 10.13422/j.cnki.syfix.2014070212.

摘要

目的：观察通络止痛方内服联合叩刺拔罐法治疗老年带状疱疹后遗神经痛（PHN）的临床疗效及对患者血清白细胞介素-2（IL-2）和肿瘤坏死因子-α（TNF-α）的影响。方法：将120例老年PHN患者随机分为对照组和观察组各60例。对照组采用盐酸阿米替林片，25 mg/次，每晚1次，口服；甲钴胺片，0.5 mg/次，3次/d，口服；氨酚曲马多片，1片/次，必要时服用；双氯芬酸钠乳膏，适量外涂患处。观察组内服通络止痛方，1剂/d，采用叩刺拔罐，隔日1次，连续治疗10次；必要时可服用氨酚曲马多片。两组疗程均为4周。记录疼痛程度、疼痛减轻时间、进行睡眠质量评定及氨酚曲马多片的使用量；检测治疗前后血清IL-2和TNF-α水平。结果：观察组治疗总有效率95.0%优于对照组的81.67%（P<0.05）；治疗后1周两组疼痛程度均较治疗前减轻（P<0.01），第2，3，4周，观察组疼痛程度评分均低于对照组（P<0.01）；治疗后1周两组睡眠质量评分均较治疗前下降（P<0.01）；观察组疼痛减轻时间少于对照组（P<0.01），氨酚曲马多片的使用量少于对照组（P<0.01）；治疗后观察组血清IL-2高于对照组，TNF-α水平低于对照组（P<0.01）。结论：络病理论指导下的叩刺拔罐法和通络止痛方内服快速减轻老年PHN患者疼痛，改善患者睡眠质量，临床疗效显著，其作用机制可能与升高IL-2、降低TNF-α水平，调节免疫功能，减轻炎症对神经功能的损伤有关。

Abstract

Objective: The purpose is to discuss the clinical effects of Tongluo Zhitong decoction united tapping and cupping methods to treat agedness ostherpetic neuralgia (PHN) and observe the influence of it on serum interleukin-2 (IL-2)and tumor necrosis factor-α(TNF-α). Method: One hundred and twenty elder patients with PHN were randomly divided into control group (60 cases) and observation group (60 cases).in control group

Control group amitriptyline hydrochloride tablets

25 mg/time

only 1 time at night

taken orally;mecobalamin tablets

0.5 mg/time

3 times/day

taken orally

paracetamol and tramadol hydrochloride tablets

1 piece/time

taken when necessary

diclofenac sodium cream

coated infected part appropriately.For patients in observation group

they took tapping acupuncture cupping

every other day

continuing using ten times;Tongluo Zhitong decoction

1 does/day

taken orally.When necessary

patients can take acetaminophen tramadol tablets.Both groups were treated for 4 weeks.Record pain degree

time of pain relief

evaluate sleep quality

and application amount of paracetamol and tramadol hydrochloride tablets. Detect the level of serum IL-2 and TNF-α before and after treatment. Result: The total treatment efficacy of the observation group was 95.0% superior to 81.67% of the control group(P<0.05). After one week of the treatment

the pain degree of the two groups were both lower than that before the treatment

at 2

4 weeks

the pain degree score of the observation group was lower than that of the control group(P<0.01). After one week of the treatment

the sleep quality score of the two groups were lower than that before the treatment(P<0.01)

the alleviative time of pain of the observation group was less than that of the control group(P<0.01)

besides

the dosage of paracetamol and tramadol hydrochloride tablets were less than that of the control group(P<0.01). Conclusion: Guided by the collateral disease theory can relief the pain of elderly PHN patients

and improve their sleep quality when tapping and cupping and Tongluo Zhitong decoction were used

which also had obvious clinical effect

and the mechanism of action may be related to improve the level of IL-2

and relief the level of TNF-α

and regulate immune function

reduce injury of neurological function which caused by inflammation.

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