WANG Xiao-ping, HAN Li, REN Gui-lin, et al. Investigation of Cryogenic Pulverization Properties of Faeces Trogopterori[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(8): 1-4.
DOI:
WANG Xiao-ping, HAN Li, REN Gui-lin, et al. Investigation of Cryogenic Pulverization Properties of Faeces Trogopterori[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(8): 1-4. DOI: 10.13422/j.cnki.syfix.2014080001.
Investigation of Cryogenic Pulverization Properties of Faeces Trogopterori
Objective: To study powder properties of Faeces Trogopterori and investigate relativity between powder properties and in vitro dissolution behavior. Method: Faeces Trogopterori was crushed by vibration type low temperature ultrafine pulverizer
sampling every 3 min
particle size
specific surface area and porosity of samples were detected;With the content of total flavonoids as index
in vitro dissolution rate of Faeces Trogopterori powder was investigated
relativity between powder properties and in vitro dissolution behavior was analyzed. Result: With increasing grinding time
particle size decreased
specific surface area and in vitrodissolution rate increased;Powder size and in vitro dissolution rate had a good correlation.Grinding time of Faeces Trogopterori selected 21 min
but particle size of d0.9 should choose was about 100 μm. Conclusion: After low-temperature ultrafine ground of Faeces Trogopterori
particle morphology and structurewas uniform with high dissolution rate
which was helpful forits subsequent evaluation of preparation process and quality control.
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Related Author
HE Yi-hang
HE Jing
ZHANG Yu-juan
TIAN Li
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MA Yue
Zheng-xin TANG
Wan-ting LI
Related Institution
Department of Chinese Medicine Information Science,Beijing University of Chinese Medicine, Beijing Key Laboratory for Production Process Control and Quality Evaluation of Traditional Chinese Medicine,Engineering Research Center of Key Technologies for Chinese Medicine Production and New Drug Development,Ministry of Education
Key Laboratory of Technologies and Applications of Ultrafine Granular Powder of Herbal Medicine,National Administration of Traditional Chinese Medicine,National and Local Joint Engineering Research Center for Ultrafine Granular Powder of Herbal Medicine,Zhongshan Zhongzhi Pharmaceutical Group Co. Ltd.
Engineering Research Center of Modern Preparation of Traditional Chinese Medicine(TCM), Ministry of Education, Innovation Research Institute of TCM, Shanghai Innovation Center of TCM Health Service, Shanghai University of TCM
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
Eye Hospital, China Academy of Chinese Medical Sciences