LI Yuan-bin, LIN Li-zhu. Chinese Medicine Multi-target to Reverse MDR Mechanisms of Lung Cancer[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(8): 232-236.
DOI:
LI Yuan-bin, LIN Li-zhu. Chinese Medicine Multi-target to Reverse MDR Mechanisms of Lung Cancer[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(8): 232-236. DOI: 10.13422/j.cnki.syfix.2014080232.
Chinese Medicine Multi-target to Reverse MDR Mechanisms of Lung Cancer
Review and analysis the progress of research in traditional Chinese herbal monomer and compound reversing lung cancer multi-drug resistance (MDR) mechanisms.Currently
traditional Chinese herbal monomer and compound achieve reversal of multidrug resistance in lung cancer primarily by reducing membrane transport proteins
decreasing tumor cell detoxification
repair
regulating signal transduction apoptosis genes
cell cycle
tumor extracellular matrix. These results indicate that traditional Chinese herbal to reverse drug resistance mechanisms of lung cancer characterized by a multi-target
with potential development value
but also for the treatment of cancer in clinical medicine provides a scientific foundation.