Studies on Pharmacodynamics and Pharmacokinetics of Anti endotoxin Shock of Shenmai Zhusheye (SMZ) in Rats[J]. Chinese journal of experimental traditional medical formulae, 2000, (3): 22-25.
Studies on Pharmacodynamics and Pharmacokinetics of Anti endotoxin Shock of Shenmai Zhusheye (SMZ) in Rats[J]. Chinese journal of experimental traditional medical formulae, 2000, (3): 22-25. DOI: 10.13422/j.cnki.syfjx.2000.03.011.
Studies on Pharmacodynamics and Pharmacokinetics of Anti endotoxin Shock of Shenmai Zhusheye (SMZ) in Rats
Anti endotoxin shock effect being taken as observed index
pharmacodynamics and pharmacokinetics of SMZ were studied in rats. The results showed that SMZ could exhibit anti endotoxin shock effect in rats. Half life(T 1/2 =1 1849h) and pharmacokinetic equation (C=6 6636×e -0 5848t ) of SMZ were obtained with the dose effect and time effect relationships in rats.
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Related Author
QIN Cai-ling1
Liu Ting1
Zhang Yi1
TAN Yu-qing1
- HUO Hai-ru1
ZHOU Min2
WEI Ping-ping2
JIANG Ting-ling1
Related Institution
Affiliated Hospital of Nanjing University of Chinese Medicine
School of Pharmacy,Liaoning University of Traditional Chinese Medicine
College of Chinese Medicine, Beijing Research Institute of Chinese Medicine, College of Life Science, Beijing University of Chinese Medicine
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Engineering Technology Research Center for Chinese Materia Medica Quality of Universities in Guangdong Province, Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica, State Administration of Traditional Chinese Medicine(TCM), School of TCM, Guangdong Pharmaceutical University