Effects of Qingxiang Pill（concentrated Pill） on Mammary Gland Hyperplasia in Rabbits and Its Mechanism

LIN Cheng-ren1; MA Xue-ying1; WANG Min1; ZONG Hong-xin2; LIU Jian-xun1

doi:10.13422/j.cnki.syfjx.2003.05.016

您当前的位置：

首页 >

文章列表页 >

Effects of Qingxiang Pill（concentrated Pill） on Mammary Gland Hyperplasia in Rabbits and Its Mechanism

更新时间：2024-09-23

- Effects of Qingxiang Pill（concentrated Pill） on Mammary Gland Hyperplasia in Rabbits and Its Mechanism
- Chinese Journal of Experimental Traditional Medical Formulae Issue 5, Pages: 35-38(2003)
- 作者机构：
  
  1.   中国中医研究院西苑医院基础医学研究室
  2.   长甲集团
  3.   中国中医研究院西苑医院基础医学研究室北京100091
  4.   上海201206
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2003.05.016
  CLC： R285.5
- Published：2003
- 稿件说明：
移动端阅览
[1]林成仁,马雪瑛,王敏,宗红心,刘建勋.青香丸(浓缩丸)对家兔乳腺增生的影响及机理研究[J].中国实验方剂学杂志,2003(05):35-38.

LIN Cheng-ren1, MA Xue-ying1, WANG Min1, et al. Effects of Qingxiang Pill（concentrated Pill） on Mammary Gland Hyperplasia in Rabbits and Its Mechanism[J]. Chinese journal of experimental traditional medical formulae, 2003, (5): 35-38.
[1]林成仁,马雪瑛,王敏,宗红心,刘建勋.青香丸(浓缩丸)对家兔乳腺增生的影响及机理研究[J].中国实验方剂学杂志,2003(05):35-38. DOI： 10.13422/j.cnki.syfjx.2003.05.016.

LIN Cheng-ren1, MA Xue-ying1, WANG Min1, et al. Effects of Qingxiang Pill（concentrated Pill） on Mammary Gland Hyperplasia in Rabbits and Its Mechanism[J]. Chinese journal of experimental traditional medical formulae, 2003, (5): 35-38. DOI： 10.13422/j.cnki.syfjx.2003.05.016.

摘要

目的 :观察青香丸（浓缩丸）对家兔实验性乳腺增生的影响。方法 :本实验给雌性未孕家兔注射苯甲酸雌二醇

复制乳腺增生病理模型

造模的同时灌胃给药

测定乳房直径和长度、乳腺体积和重量、血清性激素水平、SOD活性、MDA含量、脏器系数

镜下观察乳腺组织病理形态学变化。结果 :青香丸（浓缩丸）明显减小家兔乳房直径、长度及乳腺体积

减轻乳腺重量

减少乳腺小叶数和腺泡数 ;此外

青香丸（浓缩丸）明显降低血清E2 水平

明显增加SOD活性

抑制胸腺系数减少。结论 :青香丸（浓缩丸）具有调节性激素水平、增强清除自由基能力、减轻乳腺组织增生性病变等作用。

Abstract

Objective To study the therapeutic effect of Qingxiang Pill （concentrated Pill） on Mammary Gland Hyperplasia（MGH）. Methods Injecting rabbits with estradiol benzoate induced the model of MGH

and rabbits in the normal control received saline injection only. Changes of breast diameter and length

mammary gland volume and weight were measured. The concentrations of sex hormones

SOD

and MDA in serum were estimated. The organ coefficients were measured

too. Pathologic changes in morphology due to MGH in rabbits were observed by microscopy. Results The medicine could improve hyperplasia of mammary glands in rabbits

reduce the enlargement value of breast diameter and length

mammary gland volume and weight

decrease the numbers of acinus and lobule of mammary glands. It could also decrease E-2 level in serum

and increase serum SOD activity and the coefficient of thymus. Conclusion Qingxiang Pill （concentrated Pill） can regulate sex hormone level

increase the ability to get rid of free radicals

and improve the pathologic changes in morphology due to MGH in rabbits.

关键词

Keywords

references

Views

166

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

No data

Related Author

LIN Cheng-ren1

MA Xue-ying1

WANG Min1

ZONG Hong-xin2

LIU Jian-xun1

Related Institution

No data

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰