LIU Min 1, 2, TAN Yu-qing1, et al. Effects of Different Combinations of Four Components in Guizhi Decoction on IL-1β Stimulated PGE2 Secretion of Cerebral Microvascular Endothelial Cell[J]. Chinese journal of experimental traditional medical formulae, 2005, (5): 59-61.
LIU Min 1, 2, TAN Yu-qing1, et al. Effects of Different Combinations of Four Components in Guizhi Decoction on IL-1β Stimulated PGE2 Secretion of Cerebral Microvascular Endothelial Cell[J]. Chinese journal of experimental traditional medical formulae, 2005, (5): 59-61. DOI: 10.13422/j.cnki.syfjx.2005.05.024.
Effects of Different Combinations of Four Components in Guizhi Decoction on IL-1β Stimulated PGE2 Secretion of Cerebral Microvascular Endothelial Cell
Objective:To investigate the effects of different combinations of four components in Guizhi decoction on secretion of prostaglandin E
2
(PGE
2
) by interleukin-1β(IL-1β) stimulation in rats cerebral microvascular endothelial cell(rCMEC).These four components are among the extracted fractions of Guizhi Decoction.Methods:The amounts of PGE
2
were measured by radioimmunoassay method.Results:Twenty of the combinations significantly decreased the excessive secretion of PGE
2
induced by IL-1β in the supernatant of rCMEC.The results had the statistical signification.Conclusion:The above mentioned combinations might be the substance foundation of the Fr.A of the decoction in its dual-directional thermoregulation.
Effects of Different Combinations of Four Components in Guizhi Decoction on IL-1β Stimulated PGE Secretion of Cerebral Microvascular Endothelial Cell
Study on a Serum-pharmacology Method of a Chinese Medical Formula-I
Mechanism of Guizhi Decoction on Dual-directional Thermoregulation——Effect on AC Activity and cAMP Content in Hypothalamus of Febrile and Hypothermia Rats
活络止痛汤对炎症模型大鼠消炎作用的影响
三七有效成分对人子宫内膜细胞培养液TNF-α和IL-1β含量的影响
Related Author
LI Lan-fang1
GUO Shu-ying1
HUO Hai-ru1
HUANG Jing-yao2
JIANG Nan1
TAN Yu-qing1
2
LIU Min 1
Related Institution
Shanxi University of Traditional Chinese Medicine
Hangzhou Normal University
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences