The Influence of Sedum sarmentosum Tricin-glucoside to Lymphocyte Proliferation of Normal Mice in vitro

XIONG Yu-lan~1; WANG Yan-li~1; SUN Jian-hui~1; WEI Tai-ming~2; YAN Yu-ning~2; ZHANG Si-ju~1; ZHOU Zhong-ming~1

doi:10.13422/j.cnki.syfjx.2006.10.015

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The Influence of Sedum sarmentosum Tricin-glucoside to Lymphocyte Proliferation of Normal Mice in vitro

更新时间：2024-09-23

- The Influence of Sedum sarmentosum Tricin-glucoside to Lymphocyte Proliferation of Normal Mice in vitro
- Chinese Journal of Experimental Traditional Medical Formulae Issue 10, Pages: 29-31(2006)
- 作者机构：
  
  1. 中国中医科学院中药研究所
  2. 北京中医药大学中药学院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2006.10.015
  CLC： R285.5
- Published：2006
- 稿件说明：
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[1]熊玉兰,王彦礼,孙建辉,魏太明,阎玉凝,张思巨,周钟鸣.垂盆草小麦黄素苷体外对正常小鼠淋巴细胞增殖的影响[J].中国实验方剂学杂志,2006(10):29-31.

XIONG Yu-lan~1, WANG Yan-li~1, SUN Jian-hui~1, et al. The Influence of Sedum sarmentosum Tricin-glucoside to Lymphocyte Proliferation of Normal Mice in vitro[J]. Chinese journal of experimental traditional medical formulae, 2006, (10): 29-31.
[1]熊玉兰,王彦礼,孙建辉,魏太明,阎玉凝,张思巨,周钟鸣.垂盆草小麦黄素苷体外对正常小鼠淋巴细胞增殖的影响[J].中国实验方剂学杂志,2006(10):29-31. DOI： 10.13422/j.cnki.syfjx.2006.10.015.

XIONG Yu-lan~1, WANG Yan-li~1, SUN Jian-hui~1, et al. The Influence of Sedum sarmentosum Tricin-glucoside to Lymphocyte Proliferation of Normal Mice in vitro[J]. Chinese journal of experimental traditional medical formulae, 2006, (10): 29-31. DOI： 10.13422/j.cnki.syfjx.2006.10.015.

摘要

目的:观察垂盆草小麦黄素苷对小鼠脾脏T、B淋巴细胞转化增殖的影响。方法:采用小鼠脾细胞3H-TdR掺入法

用刀豆球蛋白（ConA）或脂多糖（LPS）刺激

测定掺入细胞DNA中3H-TdR的放射性相对数量（cpm）。结果:小麦黄素苷100

1μg/mL（终浓度）对T淋巴细胞的cpm数有非常显著的抑制作用（均P<0.001）;小麦黄素苷100μg/mL对B淋巴细胞的cpm数有非常显著的抑制作用（P<0.01）。结论:垂盆草小麦黄素苷能明显抑制正常小鼠脾脏T、B淋巴细胞增殖。

Abstract

Objective:To observe the influence of sedum sarmentosum tricin-glucoside on proliferation of spleen T and B lymphocytes of normal mice.Methods:Method of mixturing（）

H-TdR to mice spteen cell was applied.After stimulation with canavaline（ConA）or lipid polysaccharides（LPS）

the radioactive relative quantity（cpm） of（）

H-TdR in DNA in spleen cell.Results:The dosages in 100

1μg/mL（final concentration）of sedum sarmentosum tricin-ghcoside had highly significant inhibition to cpm number of T lymphocyte（P

0.001）;the dosage in 100μg/mL of sedum sarmentosum tricin-glucoside had highly significant inhibition to cpm number of B lymphocyte （P

0.01）.Conchsions:Sedum sarmentosum tricin-glucoside can obviously inhibit proliferation of spleen T and B lymphocytes of normal mice.

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ZHOU Zhong-ming1

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Related Institution

Graduate School of Beijing University of Chinese Medicine

Graduate School of China Academy of Chinese Medical Sciences

Dongfang Hospital， Beijing University of Chinese Medicine

Shenzhen Traditional Chinese Medicine（TCM） Hospital

First Affiliated Hospital， Heilongjiang University of Chinese Medicine

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