Effects of Tiaozhiqinggan Capsule on Experimental Hyperlipidemia and Fatty Liver

SHI Hai-bo~; MIAO Yan-bo; WANG Li-ping; WANG Wei

doi:10.13422/j.cnki.syfjx.2006.10.024

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Effects of Tiaozhiqinggan Capsule on Experimental Hyperlipidemia and Fatty Liver

更新时间：2024-09-23

- Effects of Tiaozhiqinggan Capsule on Experimental Hyperlipidemia and Fatty Liver
- Chinese Journal of Experimental Traditional Medical Formulae Issue 10, Pages: 56-57(2006)
- 作者机构：
  
  1. 吉林省中医中药研究院
  2. 吉林省中医中药研究院吉林长春130021
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2006.10.024
  CLC： R285.5
- Published：2006
- 稿件说明：
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[1]师海波,苗艳波,王力平,王威.调脂清肝胶囊对实验性高脂血症及脂肪肝的作用[J].中国实验方剂学杂志,2006(10):56-57+60.

SHI Hai-bo~, MIAO Yan-bo, WANG Li-ping, et al. Effects of Tiaozhiqinggan Capsule on Experimental Hyperlipidemia and Fatty Liver[J]. Chinese journal of experimental traditional medical formulae, 2006, (10): 56-57.
[1]师海波,苗艳波,王力平,王威.调脂清肝胶囊对实验性高脂血症及脂肪肝的作用[J].中国实验方剂学杂志,2006(10):56-57+60. DOI： 10.13422/j.cnki.syfjx.2006.10.024.

SHI Hai-bo~, MIAO Yan-bo, WANG Li-ping, et al. Effects of Tiaozhiqinggan Capsule on Experimental Hyperlipidemia and Fatty Liver[J]. Chinese journal of experimental traditional medical formulae, 2006, (10): 56-57. DOI： 10.13422/j.cnki.syfjx.2006.10.024.

摘要

目的:研究调脂清肝胶囊对实验性高脂血症和脂肪肝的作用。方法:采用饲饵性大鼠高血脂模型观察调脂清肝胶囊的降血脂作用

采用乙硫氨酸所致小鼠脂肪肝模型观察调脂清肝胶囊预防脂肪肝作用。结果:调脂清肝胶囊明显降低高血脂大鼠血清总胆固醇（CHO）、甘油三酯（TG）和低密度脂蛋白（LDL-C）含量

升高高密度脂蛋白（HDL-C）含量

提高（HDL-C）/（CHO）比值;明显减轻高血脂大鼠肝和腹后壁脂肪重量;对脂肪肝小鼠肝脏脂肪性改变有明显的改善作用。结论:调脂清肝胶囊具有明显的降低血脂和预防脂肪肝作用。

Abstract

Objective:To investigate the effects of Tiaozhiqinggan（TZQG） capsule on experimental hyperlipidemia in rats and fatty liver in mice.Methods:The rat hyperlipidemic model was induced by feeding caloric diet and mouse fatty liver model was induced by ethionine

and effect of different doses of TZQG capsule on reducing blood lipid and prevention of fatty liver was obsevered.Results:TZQG capsule evidently lowered the levels of CHO

and LDL-C

increased the HDLC

elevated the ratio of HDL-C and CHO in blood

and decreased the liver weight and abdominal fat of hyperlipidemic rats.It significantly improved the transformation of fatty liver of model mice.Conclusion:TZQG capsule had markedly effects on reducing blood lipid and prevention of fatty liver.

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SHI Hai-bo

MIAO Yan-bo

WANG Li-ping

WANG Wei

WANG Bin-sheng

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LIU Tong-shen

LIU Zhi-xue

Related Institution

Department of Pharmacology,Liuzhou Medical College

Department of Pharmacology,Guangxi Medical University

Chengdu University of TCM

Hospital of Chengdu University of Traditional Chinese Medicine （TCM）

Chengdu University of Traditional Chinese Medicine（TCM）

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