MA Xiao-bin~1, WANG Yang-hui~1, LIU Jian-xun~. Influence of Shenqiyixin Granule upon Hemodynamics of Chronic Heart Failure Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, (11): 27-29.
MA Xiao-bin~1, WANG Yang-hui~1, LIU Jian-xun~. Influence of Shenqiyixin Granule upon Hemodynamics of Chronic Heart Failure Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, (11): 27-29. DOI: 10.13422/j.cnki.syfjx.2007.11.009.
Influence of Shenqiyixin Granule upon Hemodynamics of Chronic Heart Failure Rats
Objective:To study the effects of Shenqiyixin Granule on hemodynamics parameters of pressure overload heart failure rat model.Methods:A model of heart failure induced by coarctation of abdominal aorta was treated in the study.The drugs were taken by oral for 4 weeks from 4 weeks to 8 weeks after operation.Results:To compere with model
Shenqiyixin Granule can decreased LVEDP、LVSP、dp/dt
max
、SAP、cardiac index、high-level of plasma AⅡ and increased lower-level K
+
in cardiac tissue.Conclusions:Shenqiyixin Granule may significantly improve hemodynemics and left ventricular function of heart failure rat.
Influence of Shenqiyixin Granule upon Hemodynamics of Chronic Heart Failure Rats
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Related Author
MA Xiao-bin1
WANG Yang-hui1
LIU Jian-xun1
ZHU Qing-lei2
WANG Shi-wen2
CHEN Yu
WANG Maolin
WANG Yun
Related Institution
State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
Jiangxi Province Key Laboratory of Traditional Chinese Medicine(TCM) Pharmacology,Institute of TCM Health Industry,China Academy of Chinese Medical Sciences
Center for Food Evaluation,State Administration for Market Regulation
Jiangxi University of Chinese Medicine
Xiyuan Hospital, China Academy of Chinese Medical Sciences