Pathogenetic Role of Poison in Wilson’s Disease

YANG Wen-ming; ZHANG Chun-hai; LI Rui-juan; DONG Ting; WANG Mei-xia; YANG Xing-tao; BAO Yuan-cheng

doi:10.13422/j.cnki.syfjx.2009.11.004

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Pathogenetic Role of Poison in Wilson’s Disease

更新时间：2024-09-23

- Pathogenetic Role of Poison in Wilson’s Disease
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 15, Issue 11, Pages: 109-111(2009)
- 作者机构：
  
  安徽中医学院第一附属医院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2009.11.004
  CLC： R277.7
- Published：2009
- 稿件说明：
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[1]杨文明,张春海,李瑞娟,董婷,汪美霞,杨兴涛,鲍远程.毒邪在肝豆状核变性致病中的作用[J].中国实验方剂学杂志,2009,15(11):109-111.

YANG Wen-ming, ZHANG Chun-hai, LI Rui-juan, et al. Pathogenetic Role of Poison in Wilson’s Disease[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(11): 109-111.
[1]杨文明,张春海,李瑞娟,董婷,汪美霞,杨兴涛,鲍远程.毒邪在肝豆状核变性致病中的作用[J].中国实验方剂学杂志,2009,15(11):109-111. DOI： 10.13422/j.cnki.syfjx.2009.11.004.

YANG Wen-ming, ZHANG Chun-hai, LI Rui-juan, et al. Pathogenetic Role of Poison in Wilson’s Disease[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(11): 109-111. DOI： 10.13422/j.cnki.syfjx.2009.11.004.

摘要

目的:目的:探讨毒邪在肝豆状核变性发病中的地位。方法:阐述传统医学及现代医学对毒邪的认识

毒邪对机体造成的损害

并重点阐述毒邪在肝豆状核变性致病中的作用。结果:毒邪是临床上常见的致病之邪

它可造成机体多方面的损害

肝豆状核变性是一全身性疾病

涉及多个系统、器官

铜浊毒邪内聚体内是其发病的病理生理学基础

也是从毒论治的依据所在。结论:毒邪在肝豆状核变性致病中起着十分重要的作用

铜毒内蓄

损伤肝络、脑络以及全身的络脉是肝豆状核变性的病机关键

从毒论治是肝豆状核变性的临床治疗的重要途径。

Abstract

Objective:To investigate the pathogenetic role of poison in wilson’s disease.Methods: The understandings of poison from both Chinese traditional medicine and western medicine were collected

Damages to organism by poison

especially the pathogenetic role of poison in wilson’s disease

were discussed.Results: Poison is a common pathogenetic factor clinically and may cause damage to many organs.Wilson’s disease is a systemic disease which refers to multi-systems and organs

the accumulation of copper poison in the body is its pathophysiologic basis

and also the foundation of therapeutical method for disintoxicating.Conclusion: Poison plays a very important role in the pathogenetic factors for Wilson’s disease.The key pathogenesis of Wilson’s disease is the accumulation of copper poison in the body

and it cause the damage to the collaterals of liver

the collaterals of brain and the whole body’s collaterals.The direct disintoxication is an important method of treating Wilson’s disease.

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Related Author

YANG Wen-ming

ZHANG Chun-hai

LI Rui-juan

DONG Ting

WANG Mei-xia

YANG Xing-tao

BAO Yuan-cheng

Nan-nan QIAN

Related Institution

Graduate School，Anhui University of Chinese Medicine

The First Affiliated Hospital of Anhui University of Chinese Medicine

Key Laboratory of Xin'an Medicine Ministry of Education

TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province

Hospital of Chengdu University of TCM

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