WANG Lian-rong~. Experimental Studies on the Treatment of Type Ⅱ Collagen Induced Arthritis with Da-Fang-Feng-Tang[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(2): 100-103.
WANG Lian-rong~. Experimental Studies on the Treatment of Type Ⅱ Collagen Induced Arthritis with Da-Fang-Feng-Tang[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(2): 100-103. DOI: 10.13422/j.cnki.syfjx.2010.02.023.
Experimental Studies on the Treatment of Type Ⅱ Collagen Induced Arthritis with Da-Fang-Feng-Tang
Objective:To observe the effect of Da-Fang-Feng-Tang(DFFT) in treating of Rheumatoid Arthritis(RA).Methods: The animal model of type Ⅱ collagen induced arthritis was used.Granules of the DFFT extract were administered by gastric gavage
studying in genetics
immunology
physiology and clinical.Results: The results indicated a higher onset rate
a severer redness and swelling for arthritic limb and a longer time of clinic manifestation in contract group than treated group
and the IgG level in sera was significantly increased compared contract group to treated group(P<0.05).The gene express of IL-1
TNF-α and IFN-γ were higher in contract group.Conclusion: DFFT express obviously suppressive function on model of type Ⅱ collagen induced arthritis in NIH mouse
and support the belief that DFFT is effective in treating human RA.
Experimental Studies on the Treatment of Type Ⅱ Collagen Induced Arthritis with Da-Fang-Feng-Tang
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Related Author
WANG Lian-rong
WU Wei-kang
CHEN Yuhang
ZHANG Ye
CHEN Hong
ZHANG Ziwei
WU Liqun
HUO Jingwei
Related Institution
Dongfang Hospital, Beijing University of Chinese Medicine
Yunnan Provincial Hospital of Traditional Chinese Medicine
School of Clinical Medicine,Beijing University of Chinese Medicine
Beijing Key Laboratory of Chinese Materia Pharmacology,National Clinical Research Center of Traditional Chinese Medicine for Cardiovascular Diseases,Institute of Basic Medical Sciences, Xiyuan Hospital,China Academy of Chinese Medical Sciences