REN Jun-guo, MA Xiao-bin, LIN Cheng-ren, et al. Protective Effect of Jiawei Shengmaisan Against Acute Myocardial Ischemia/Reperfusion Injury in Rats[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(2): 78-80.
REN Jun-guo, MA Xiao-bin, LIN Cheng-ren, et al. Protective Effect of Jiawei Shengmaisan Against Acute Myocardial Ischemia/Reperfusion Injury in Rats[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(2): 78-80. DOI: 10.13422/j.cnki.syfjx.2010.02.038.
Protective Effect of Jiawei Shengmaisan Against Acute Myocardial Ischemia/Reperfusion Injury in Rats
Objective:To investigate protective effect of Jiawei Shengmaisan against acute myocardial ischemia/reperfusion injury in rats.Methods:The acute myocardial ischemia/reperfusion injury in rats was induced by ligating the anterior descending coronary artery in SD rats and administered different dosage jiawei shengmaisan decotion into duodenum
myocardial infarction degree(MID) was calculated by detcting myocardial infarction area with nitroblue tetrazolium(NBT) assay
SOD activities and MDA、NO contents were detected with biochemical assay.Results: Jiawei shengmaisan can significantly decreased MID and MDA contents in serum
increased SOD activities and NO contents in serum.Conclusions: The results showed that Jiawei shengmaisan has protective effect against acute myocardial ischemia/reperfusion injury in rats
which may be relate to its antioxygen action and NO.
Protective Effect of Jiawei Shengmaisan Against Acute Myocardial Ischemia/Reperfusion Injury in Rats
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Related Author
LIU Jian-xun
LI Jun-mei
WANG Min
LI Hong-hai
WANG Yang-hui
LIN Cheng-ren
MA Xiao-bin
REN Jun-guo
Related Institution
Hebei Industrial Technology Institute for Traditional Chinese Medicine Preparation
Hebei Provincial Hospital of Chinese Medicine
Hebei University of Chinese Medicine
Health Supervision Institute of Huaiyin District
Shandong University of Chinese Medicine Affiliated Hospital