Study on the Calcium Ion Dissolution Regularity of Different Compatibility in Baihu Decoction by ICP-AES

MA Qiang1; SU Kun2; SHENG Zhen-hua1; WU Jun-jin1; LU Lin1; GE Er-ning1; SU Yan3

doi:10.13422/j.cnki.syfjx.2010.05.029

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Study on the Calcium Ion Dissolution Regularity of Different Compatibility in Baihu Decoction by ICP-AES

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- Study on the Calcium Ion Dissolution Regularity of Different Compatibility in Baihu Decoction by ICP-AES
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 16, Issue 5, Pages: 86-88(2010)
- 作者机构：
  
  1. 浙江中医药大学分析测试中心
  2. 内蒙古科技大学包头医学院药学院
  3. 内蒙古科技大学包头医学院基础学院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2010.05.029
  CLC： R283
- Published：2010
- 稿件说明：
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[1]马强,苏琨,盛振华,吴君金,卢林,葛尔宁,苏燕.ICP-AES法研究不同配伍条件下白虎汤中钙离子溶出规律[J].中国实验方剂学杂志,2010,16(05):86-88.

MA Qiang1, SU Kun2, SHENG Zhen-hua1, et al. Study on the Calcium Ion Dissolution Regularity of Different Compatibility in Baihu Decoction by ICP-AES[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(5): 86-88.
[1]马强,苏琨,盛振华,吴君金,卢林,葛尔宁,苏燕.ICP-AES法研究不同配伍条件下白虎汤中钙离子溶出规律[J].中国实验方剂学杂志,2010,16(05):86-88. DOI： 10.13422/j.cnki.syfjx.2010.05.029.

MA Qiang1, SU Kun2, SHENG Zhen-hua1, et al. Study on the Calcium Ion Dissolution Regularity of Different Compatibility in Baihu Decoction by ICP-AES[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(5): 86-88. DOI： 10.13422/j.cnki.syfjx.2010.05.029.

摘要

目的:通过研究不同配伍条件下药液中钙离子溶出量变化

探讨白虎汤的配伍规律。方法:采用电感耦合高频等离子体原子发射光谱（ICP-AES）法测定白虎汤中各单味药及不同配伍条件下药液中Ca2+溶出量。结果:各单味药物中均含钙

其中石膏含钙量最高

其次为知母和甘草

粳米含钙量最低。石膏与甘草配伍能增加药液中Ca2+溶出量

石膏与粳米配伍对药液中Ca2+溶出量影响不大

石膏与知母配伍可降低药液中Ca2+溶出量

全方配伍条件下药液中Ca2+溶出量增加。结论:这充分的体现了中医方剂组方原则

石膏为君药、知母为臣药发挥解热作用

甘草为佐药

抑制了部分知母对石膏中Ca2+溶出的负面作用

加强了君臣药的解热作用。研究结果显示

中药配伍有其规律性和合理性

这对进一步研究中药矿物药物在复方中药理作用有重要的指导意义。

Abstract

Objective:To study the soluble calcium ion content of different compatibility of Baihu Decoction and to discuss the compatibility regularity of Baihu Decoction. Method:ICP-AES was used to detect the content of soluble calcium ion of each single and different compatibility herbs in Baihu Decoction. Result:The results showed that all of herbs in Baihu Decoction contained calcium. Gypsum had the highest content of calcium

followed by Rhizoma Anemarrhenae and Licoroce

Rice had the lowest. The calcium ion dissolution content was increased when Gypsum and Licoroce compatibled together; but not influenced by Gypsum and Rice and reduced by Gypsum and Rhizoma Anemarrhenae. Also the calcium ion content was increased when all herbs of Baihu Decoction compatibled together. Conclusion:It reflected the prescription principles of traditional Chinese medicine sufficiently. Gypsum is the monarch drug and Rhizoma Anemarrhenae is the minister drug

both of them have antipyretic effect. Licorice is assistant drug to restrain some Rhizoma Anemarrhenae’s negative effects on the calcium ion solubility of gypsum

and increase the antipyretic effect of the monarch drug and minister drug. So the compatibility of traditional Chinese medicine has its own regularity and rationality

it has important guiding significance to the further research on the pharmacological effects of mineral drugs in Chinese herbal compound.

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Related Author

MA Qiang

SU Kun

SHENG Zhen-hua

WU Jun-jin

LU Lin

GE Er-ning

SU Yan

LI Xiao-jing

Related Institution

College of Agronomy， Henan Agricultural University

Henan Provincial Engineering Technology Research Center for Quality Control and Evaluation of Traditional Chinese Medicine， Henan University of Chinese Medicine

Beijing University of Chinese Medicine

School of Traditional Chinese Medicine（TCM），Shanghai University of TCM

School of Chinese Materia Medica， Beijing University of Chinese Medicine

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