Effect of Radix Astragali Injection on Creatine Kinase and Isoenzyme of Creatine Kinase Level in Rat Serum After Two Kind of Exhausting Exercises

LI Yong-feng; HAN Yong; GUO Yong-li; WANG Chuan-jun; LI Ye

doi:10.13422/j.cnki.syfjx.2010.06.040

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Effect of Radix Astragali Injection on Creatine Kinase and Isoenzyme of Creatine Kinase Level in Rat Serum After Two Kind of Exhausting Exercises

更新时间：2024-09-23

- Effect of Radix Astragali Injection on Creatine Kinase and Isoenzyme of Creatine Kinase Level in Rat Serum After Two Kind of Exhausting Exercises
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 16, Issue 6, Pages: 224-226(2010)
- 作者机构：
  
  山东体育学院日照校区基础理论系
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2010.06.040
  CLC： R285.5
- Published：2010
- 稿件说明：
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[1]李永峰,韩勇,郭勇力,王传军,李晔.黄芪注射液对2种力竭运动大鼠血清肌酸激酶及其同工酶活性的影响[J].中国实验方剂学杂志,2010,16(06):224-226+230.

LI Yong-feng, HAN Yong, GUO Yong-li, et al. Effect of Radix Astragali Injection on Creatine Kinase and Isoenzyme of Creatine Kinase Level in Rat Serum After Two Kind of Exhausting Exercises[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(6): 224-226.
[1]李永峰,韩勇,郭勇力,王传军,李晔.黄芪注射液对2种力竭运动大鼠血清肌酸激酶及其同工酶活性的影响[J].中国实验方剂学杂志,2010,16(06):224-226+230. DOI： 10.13422/j.cnki.syfjx.2010.06.040.

LI Yong-feng, HAN Yong, GUO Yong-li, et al. Effect of Radix Astragali Injection on Creatine Kinase and Isoenzyme of Creatine Kinase Level in Rat Serum After Two Kind of Exhausting Exercises[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(6): 224-226. DOI： 10.13422/j.cnki.syfjx.2010.06.040.

摘要

目的:探讨黄芪注射液对两种力竭运动大鼠血清肌酸激酶（CK）及其同工酶的影响

为减轻运动性肌肉损伤寻找有效的方法。方法:将50只大鼠随机均分为5组

各10只:安静对照组、一次性力竭运动组、多次力竭运动组、服药+一次性力竭运动组、服药+多次力竭运动组。经过4周的实验后

测血清CK及其同工酶的含量。结果:一次力竭和多次力竭大鼠血清CK及其同工酶活性显著增高（P<0.01）

黄芪注射液对一次力竭和多次力竭大鼠血清CK及其同工酶活性有降低作用（P<0.01）。结论:黄芪注射液对减轻2种力竭运动引起的肌肉损伤均有很好的作用。

Abstract

Objective:In order to search potent means for exercise-induced muscle damage

effect of Radix Astragali injection on serum creatine kinase（CK） and isoenzyme of creatine kinase（CK-MM） level in rats after two kind of Exhausting Exercises was observed.Method:50 Wister Rats were randomLy divided into 5 group:normal control group（n = 10）

once exhausting exercise group（n = 10）

multiple exhausting exercises group（n = 10）

Radix Astragali injection filled the stomach and once exhausting exercise group（n = 10）

Radix Astragali injection filled the stomach and multiple exhausting exercises group（n = 10）.After 4 weeks test

serum CK and CK-MM were tested.Result:Afer exhausting exercise

CK and CK-MM in blood serum as well as were higher than that in normal control group（P < 0.01）.the change was prevented by Radix Astragali injection（P < 0.01）.Conclusion:Radix Astragali injection may help reduce exercise-induced muscle damage afer two kind of exhausting exercises.

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