GUO Jie1, ZHAO Hai-xia2, YAN Yan1, et al. Effect of Sulfur Fumigated Dioscorea opposita on Oxidative Stress and ATP Enzyme in Liver of Rats[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(11): 150-153.
GUO Jie1, ZHAO Hai-xia2, YAN Yan1, et al. Effect of Sulfur Fumigated Dioscorea opposita on Oxidative Stress and ATP Enzyme in Liver of Rats[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(11): 150-153. DOI: 10.13422/j.cnki.syfjx.2010.11.048.
Effect of Sulfur Fumigated Dioscorea opposita on Oxidative Stress and ATP Enzyme in Liver of Rats
Objective:To investigate the influence of Sulfur fumigated Dioscorea opposita on antioxidation
Ca2 + Mg2 +-ATPase
Na + K +-ATPase in liver of rats.Method:Wistar rats were divided randomLy into 4 groups
one control and three experimental groups administrated diets mixed with concentrated extractions from unfumigated
commercial and sulfur fumigated D.opposita respectively.The activities of Ca2 + Mg2 +-ATPase and Na + K +-ATPase and the level of MDA and activities of SOD and GSH-Px 14 weeks after treatment were measured and observe liver framework of organization change.Result:Results showed that activities of GSH-Px 14 weeks after treatment of un-fumigated
commercial D.opposita were significantly increased compared with control group;commercial D.opposi-ta enhanced the activities of Na + K +-ATPase.Conclusion:The long-term use of D.opposita has the possibility to cause lipid peroxidation and change the activities of Na + K +-ATPase in liver.
Effect of Sulfur Fumigated on Oxidative Stress and ATP Enzyme in Liver of Rats
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Related Author
GUO Jie
ZHAO Hai-xia
YAN Yan
CHENG Dong
XIE Wei
YAO Wen-huan
ZHOU Yun
YU Songren
Related Institution
Research Center for Differentiation and Development of Traditional Chinese Medicine (TCM) Basic Theory/Jiangxi Province Key Laboratory of Biological Etiologies of TCM/First-Level Discipline Platform of Chinese and Western Integrative Medicine/Experimental Animal and Scientific Technology Center of Jiangxi University of Chinese Medicine/School of Pharmacy, Jiangxi University of Chinese Medicine
Graduate School, Hunan University of Chinese Medicine
Wuhan Hospital of Traditional Chinese Medicine
Affiliated Hospital of Jiangxi University of Chinese Medicine
Affiliated Hospital of Hunan Academy of Chinese Medicine