Technics of Extraction of Gegen Qinlian Dispensing Granule

CHEN Li-hong1; TANG Yu-ping2; WANG Qiang3

doi:10.13422/j.cnki.syfjx.2010.14.020

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Technics of Extraction of Gegen Qinlian Dispensing Granule

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- Technics of Extraction of Gegen Qinlian Dispensing Granule
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 16, Issue 14, Pages: 4-8(2010)
- 作者机构：
  
  1. 南京中医药大学药学院
  2. 南京中医药大学江苏省方剂研究重点实验室
  3. 中国药科大学中药分析教研室
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2010.14.020
  CLC： R283.6
- Published：2010
- 稿件说明：
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[1]陈丽红,唐于平,王强.葛根芩连配方颗粒提取工艺研究[J].中国实验方剂学杂志,2010,16(14):4-8.

CHEN Li-hong1, TANG Yu-ping2, WANG Qiang3. Technics of Extraction of Gegen Qinlian Dispensing Granule[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(14): 4-8.
[1]陈丽红,唐于平,王强.葛根芩连配方颗粒提取工艺研究[J].中国实验方剂学杂志,2010,16(14):4-8. DOI： 10.13422/j.cnki.syfjx.2010.14.020.

CHEN Li-hong1, TANG Yu-ping2, WANG Qiang3. Technics of Extraction of Gegen Qinlian Dispensing Granule[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(14): 4-8. DOI： 10.13422/j.cnki.syfjx.2010.14.020.

摘要

目的:研究葛根芩连配方颗粒提取的优化工艺。方法:分别以葛根、黄芩及黄连的有效成分葛根素、黄芩苷及盐酸小檗碱为指标

用正交试验设计法对葛根芩连配方颗粒的提取工艺进行优化。结果:葛根芩连配方颗粒的最佳工艺为:葛根、黄芩和甘草3药合煎

黄连单煎;葛根、黄芩和甘草3药合煎的提取工艺为加水量第1煎10倍

第2煎8倍;提取1.5 h;提取2次。黄连单煎的提取工艺为加水量第1煎12倍

第2煎10倍;提取1.5 h;提取2次。结论:葛根、黄芩和甘草3药合煎

黄连单煎后各成分的提取率较高

保证了葛根芩连配方颗粒的质量。

Abstract

Objective:To study the optimal technics of the extraction of Gegen Qinlian dispensing granule.Method:Taking puerarin

baicalin and berberine as the index

a method of orthogonal experimental design was ap-plied to optimizing the technics of extraction.Result:The optimal extraction technology of Gegen Qinlian dispensing granule was to extract Radix Puerariae Lobatae

Radix Scutellariae

and Radix et Rhizoma Glycyrrhizae Praeparata cum Melle together and to extract Rhizoma Coptidis alone.Radix Puerariae Lobatae

Radix Scutellariae

and Radix et Rhizoma Glycyrrhizae Praeparata cum Melle were weighed in proportion

and were extracted for 1.5 h twice with 10 times and 8 times water

respectively.Rhizoma Coptidis was weighed and extracted for 1.5 h twice with 12 times and 10 times water

respectively.Conclusion:The extraction of the active components of puerarin

baicalin and berberine from Gegen Qinlian dispensing granule was satisfactory.

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