LEI Yang, XIA Xin-hua, CHEN Xi. Study on Acohol Extraction Process of Weikan Tablets[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(15): 28-30.
LEI Yang, XIA Xin-hua, CHEN Xi. Study on Acohol Extraction Process of Weikan Tablets[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(15): 28-30. DOI: 10.13422/j.cnki.syfjx.2010.15.018.
Study on Acohol Extraction Process of Weikan Tablets
摘要
目的:探索胃康片最佳醇提工艺条件。方法:以浸膏得率和盐酸小檗碱含量为评价指标
采用正交设计法对醇提工艺条件进行优选。结果:最佳提取工艺为:以80%乙醇为溶剂
浸泡1.5 h
提取2次
加醇量分别为8
6倍量
提取时间分别为2.5
2.0 h。结论:优选的提取工艺稳定可行。
Abstract
Objective: To seek the optimum alcohol extraction conditions of Weikan tablets.Method:The extraction conditions were optimized by orthogonal tests with the extract yield and the amount of the extracted hydrochloride berberine as index.Result: The optimum extraction process was as follows: soaking in alcohol for 1.5 h
extracting two times
adding alcohol for 8
6 times and extracting for 2.5
2.0 h respectively.Conclusion: The optimum extraction process was stable and practicable in manufacture.
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Related Author
LEI Yang
XIA Xin-hua
CHEN Xi
BU Shui
LIN Hua-qing
DENG Hong
LI Xin-wei
BU Shui
Related Institution
Guangzhou Provincial Key Laboratory of Advanced Drug Delivery
Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences
Medical School, Lijiang Culture and Tourism College
Key Laboratory of Modern Preparation of Traditional Chinese Medicine (TCM),Ministry of Education,Jiangxi University of Chinese Medicine