LIU Yu-bin1, WANG Hui1, TANG Xiao-feng1, et al. Evaluation of Effect of Buzhong Yiqi Tang on Rats of Qi-deficiency with Fever by Grey Relational Clustering Method[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(18): 124-128.
LIU Yu-bin1, WANG Hui1, TANG Xiao-feng1, et al. Evaluation of Effect of Buzhong Yiqi Tang on Rats of Qi-deficiency with Fever by Grey Relational Clustering Method[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(18): 124-128. DOI: 10.13422/j.cnki.syfjx.2010.18.020.
Evaluation of Effect of Buzhong Yiqi Tang on Rats of Qi-deficiency with Fever by Grey Relational Clustering Method
Objective:To investigate the utilization of grey relational clustering method in evaluating the treatment of Buzhong Yiqi Tang on rats with Qi-deficiency and fever.Method:SD rats were randomly divided into normal group
Qi-deficiency group
Qi-deficiency and fever group
positive control group(aspirin)
high-dose Buzhong Yiqi Tang group
middle-dose Buzhong Yiqi Tang group and low-dose Buzhong Yiqi Tang group.Swimming strain method and dietary restriction method were utilized to establish the rat model of Qi-deficiency
addition to normal group and Qi-deficiency group
in each group we established the rat model of Qi-deficiency and fever by intraperitoneal injection of LPS.The difference ΔT between rats’measuring temperature and BBT of each group was then compared.Finally
using gray relational clustering method a comprehensive evaluation of the experimental results was conducted.Result:As for the treatment on rats with Qi-deficiency and fever
aspirin group and high-dose Buzhong Yiqi Tang group were the best
middle-dose Buzhong Yiqi Tang group and low-dose Buzhong Yiqi Tang group ranked behind.Conclusion:Grey relational clustering method can evaluate the effect of Buzhong Yiqi Tang on rats of Qi-deficiency with fever objectively and fairly.
Evaluation of Effect of Buzhong Yiqi Tang on Rats of Qi-deficiency with Fever by Grey Relational Clustering Method
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Related Author
XUE Man-qing
TANG Xiao-feng
WANG Hui
LIU Yu-bin
Peng-fei KONG
Xian-peng WEI
Xue-gui TANG
Ying ZHANG
Related Institution
Affiliated Hospital of North Sichuan Medical College
North Sichuan Medical College
Liaoning University of Traditional Chinese Medicine
Jiangxi University of Traditional Chinese Medicine ( TCM)
The Affiliated Hospital of Jiangxi University of TCM