Comparative Study on Properties of Angelica in Ultrafine Powder and Common Powder

CHEN Xu-long1; ZHAO Guo-wei1; LIAO Zhen-gen1; LIANG Xin-li1; WANG Guang-fa1; ZHU Jing-yun1; ZHAO Li-jun1; JIANG Qie-ying2

doi:10.13422/j.cnki.syfjx.2010.18.053

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Comparative Study on Properties of Angelica in Ultrafine Powder and Common Powder

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- Comparative Study on Properties of Angelica in Ultrafine Powder and Common Powder
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 16, Issue 18, Pages: 1-5(2010)
- 作者机构：
  
  1. 江西中医学院现代中药制剂教育部重点实验室
  2. 江西中医学院成人教育学院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2010.18.053
  CLC： R283
- Published：2010
- 稿件说明：
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[1]陈绪龙,赵国巍,廖正根,梁新丽,王光发,祝婧云,招丽君,蒋且英.当归超微粉体和普通粉体的粉体学性质比较[J].中国实验方剂学杂志,2010,16(18):1-5.

CHEN Xu-long1, ZHAO Guo-wei1, LIAO Zhen-gen1, et al. Comparative Study on Properties of Angelica in Ultrafine Powder and Common Powder[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(18): 1-5.
[1]陈绪龙,赵国巍,廖正根,梁新丽,王光发,祝婧云,招丽君,蒋且英.当归超微粉体和普通粉体的粉体学性质比较[J].中国实验方剂学杂志,2010,16(18):1-5. DOI： 10.13422/j.cnki.syfjx.2010.18.053.

CHEN Xu-long1, ZHAO Guo-wei1, LIAO Zhen-gen1, et al. Comparative Study on Properties of Angelica in Ultrafine Powder and Common Powder[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(18): 1-5. DOI： 10.13422/j.cnki.syfjx.2010.18.053.

摘要

目的:比较当归超微粉体和普通粉体的粉体学性质

为超微粉粹应用于当归提供试验依据。方法:通过测定当归粉体的粒径及分布、吸湿性、粉体的形貌结构等粉体学特征和体外溶出行为

研究当归粉体的粒径对其粉体学特性、含量和体外溶出行为的影响。结果:随当归粉体粒度的减小

比表面积及孔容和吸湿性增加

流动性变弱

4种粉体中阿魏酸含量大小顺序为普通粉>微粉Ⅰ>微粉Ⅱ>微粉Ⅲ

但是随着粉碎程度的加强

微粉Ⅱ中的阿魏酸溶出速率、累积溶出率和溶出总量均高于其它粒径级别的当归粉体。结论:适度的微粉化能促进当归有效成分的溶出。

Abstract

Objective:To compare the powder properties between common powder and micropowders of Angelica to provide experimental evidence for the superfine grinding application.Method:Morphology structure

hygroscopic property

liquidity

surface area and porosity of Angelica powders were investigated;the contents and the dissolution of ferulic acid of Angelica powders were determined by HPLC.Result: With the decreasing of particle size of powders

the surface area

pore volume and moisture increased

and the liquidity decreased;the contents of ferulic acid from four Angelica powders were in the order of: common powder > ultrafine powder I > ultrafine powder II > ultrafine powder III;but with the crushing level increased

dissolution rate and the total dissolution of the ultrafine powder II was higher than levels of particle size in other angelica powder.Conclusion: An appropriate degree of micronization is helpful for the dissolution of the active components in Angelica.

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Related Author

JIANG Qie-ying

ZHAO Li-jun

ZHU Jing-yun

WANG Guang-fa

LIANG Xin-li

LIAO Zhen-gen

ZHAO Guo-wei

CHEN Xu-long

Related Institution

Jiangxi University of Traditional Chinese Medicine

Key Laboratory for Modern Preparation of Traditional Chinese Medicine,Ministry of Education

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