Objective: To investigate the effect of Qishenyiqi pills on ventricular structure and cardiac functions of patients with blood-stasis syndrome after myocardial infarction（MI）.Method: Seventy-eight cases meeting the diagnostic criteria for MI and matched criteria were chosen and divided randomly into two groups: a treatment group and a control group.Animals in the control group were treated with routine medicine and those in the treatment group were treated additionally by Qishenyiqi pills.Effects in both groups were observed for 1 year.Changes of scores for evaluating symptoms by traditional Chinese medicine（TCM） and changes of heart structure and its functions shown by echocardiography were observed before and after the treatment in both groups.Plasma levels of N-terminal pro-brain natriuretic peptide in the two groups were measured by ELISA before and after the treatment

and adverse reactions were also observed.Result: Symptom scores of the two groups decreased after treatment and the scores in the treatment group were significantly lowered than those in the control group（P < 0.05）.After treatment

the total effective rate of symptom scores evaluated by TCM was 89.5% in the treatmentgroup

and that in the control group was 75%

showing the efficiency in the treatment group was superior to that in the control group.The left ventricular internal diameter at end-systole（VESD） in the treatment group and control group were both improved

indicating the internal diameter and the volume of ventricle reflecting the thickness of the ventricle structure decreased.After the treatment

the left ventricle end-diastolic volume was significantly lowered in the treatment group

compared with that in the control group（P < 0.05）

suggesting the volume of ventricle reflecting the thickness of the ventricle significantly decreased.The stroke volume

effective cardiac output

cardiac index and left ventricular ejection fraction in the treatment group were significantly developed after the treatment

indicating obvious improvement of cardiac contraction function and increase in cardiac output with a significant difference

compared with those in the control group（P < 0.05）.After the treatment

the level of plasma brain natriuretic peptide（NT-proBNP）

the marker of left ventricular thickness in the treatment group was significantly lowered than that in the control group

which was in accord with the decreasing trend shown by ultrasonic cardiograph

and the marker was more sensitive.Conclusion: Qishenyiqi pills can improve ventricular remodeling and cardiac functions of patients with Qi deficiency and blood stasis syndrome after MI.