XU Dan-yang, CHEN Pei-dong, ZHANG Li, et al. Study on Chemical Constituents of Scutellaria baicalensis[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(1): 78-80.
XU Dan-yang, CHEN Pei-dong, ZHANG Li, et al. Study on Chemical Constituents of Scutellaria baicalensis[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(1): 78-80. DOI: 10.13422/j.cnki.syfjx.2011.01.036.
Study on Chemical Constituents of Scutellaria baicalensis
Objective: Study the chemical constituents of the radixs of Scutellaria baicalensis.Method: Use column chromatography and preparation thin layer chromatography to separate and purify the compounds.Structure analysis were carried out by buclear magnetic resonance(NMR) technology.Result: Ten compounds were separated and purified from chloroform parts of S.baicalensis
and identified as β-sitosterol(1)
benzoic acid(2)
oroxylin-A(3)
wogonin(4)
baicalein(5)
dihydroroxylinA(6)
skullcapflavone-Ⅱ(7)
tenaxin-Ⅰ(8)
5-methoxy-7-hydroxyflavonone(9)
5
7
2′
5′-tetrahydroxy-8
6′-dimethoxyflavone(10).Conclusion: Compound(9) were discovered from S.baicalensis for the first time.