Objective:To observe the effects of Rauwolfia verticillata（Lour.）Baill.var.hainanensis Tsiang（R.verticillata） on inflammation.Method: Inflammation models were established by 2

4-dinitrochlorobenzene-induced ear swelling and the swelling-induced changes of skin capillary permeability in mice

albumen-induced toe swelling in rats

and tampon embedding-caused granuloma in rats

respectively.Effects of the aqueous extract from roots of R.verticillata on the inflammation were observed.Result:The aqueous extract of 1 725 mg·kg-1 in dose inhibited 2

4-dinitrochlorobenzene-inducing mouse ear swelling by 69.64%（P<0.01）

and it could also significantly inhibit accentuation of membrane permeability（P<0.05）.The inhibitory effect of the aqueous extract of 1 194 mg·kg-1 in dose was similar to that of 12.6 mg·kg-1 of aspirin（P<0.01） in inhibiting abnormal skin capillary permeability induced by albumen-induced rat toe swelling（P<0.05）

and it was higher than the inhibition produced by 12.6 mg·kg-1 of aspirin in inhibiting tampon embedding-induced granuloma formation in rats（P<0.05）.Conclusion:The aqueous extract from roots of R.verticillata（Lour.）Baill.var.hainanensis Tsiang performed significant anti-inflammatory effects on animals.