Effects of Huixiangzhizhu Soup on Abdominal Verticalposition Plain Film Radiography in Rats with Adhesive Intestinal Obstruction

TANG Xiao-yong1; WANG Dong-hong2; SHENG Li1; LIU Yuan-jie1; LI Liang3; WANG Zi-li1

doi:10.13422/j.cnki.syfjx.2011.02.055

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Effects of Huixiangzhizhu Soup on Abdominal Verticalposition Plain Film Radiography in Rats with Adhesive Intestinal Obstruction

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- Effects of Huixiangzhizhu Soup on Abdominal Verticalposition Plain Film Radiography in Rats with Adhesive Intestinal Obstruction
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 2, Pages: 199-202(2011)
- 作者机构：
  
  1. 甘肃省中医院
  2. 兰州军区兰州总医院医务科
  3. 甘肃中医学院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2011.02.055
  CLC： R285.5
- Published：2011
- 稿件说明：
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[1]唐晓勇,王东红,盛丽,柳渊洁,李亮,王自立.茴香枳术汤对大鼠粘连性肠梗阻腹部立位平片的影响[J].中国实验方剂学杂志,2011,17(02):199-202.

TANG Xiao-yong1, WANG Dong-hong2, SHENG Li1, et al. Effects of Huixiangzhizhu Soup on Abdominal Verticalposition Plain Film Radiography in Rats with Adhesive Intestinal Obstruction[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(2): 199-202.
[1]唐晓勇,王东红,盛丽,柳渊洁,李亮,王自立.茴香枳术汤对大鼠粘连性肠梗阻腹部立位平片的影响[J].中国实验方剂学杂志,2011,17(02):199-202. DOI： 10.13422/j.cnki.syfjx.2011.02.055.

TANG Xiao-yong1, WANG Dong-hong2, SHENG Li1, et al. Effects of Huixiangzhizhu Soup on Abdominal Verticalposition Plain Film Radiography in Rats with Adhesive Intestinal Obstruction[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(2): 199-202. DOI： 10.13422/j.cnki.syfjx.2011.02.055.

摘要

目的:观察茴香枳术汤对大鼠粘连性肠梗阻腹部立位平片的影响

为深入探讨茴香枳术汤对粘连性肠梗阻的作用机制提供实验依据。方法:制备大鼠粘连性肠梗阻模型

随机分为正常组、模型组、大承气汤组、茴香枳术汤低、中、高剂量组。正常组和模型组两组灌服生理盐水0.01 mL·g-1

DS组灌服1.43 g·mL-1大承气汤0.01 mL·g-1

HX-SL

HX-SM

HX-SH 3组分别灌服1.13

2.25

3.38 g·mL-1的茴香枳术汤汤液0.01 mL·g-1。给予相应药物治疗

分别于治疗后第3

7天

共3个时间点

每时间点6只;腹腔麻醉后

拍摄腹部立位X线平片

观察肠梗阻的变化。结果:与正常组比较

模型组大鼠有大量积气积液

可见明显的气液平面

肠管扩张;与模型组比较

大承气汤组、茴香枳术汤低剂量组、茴香枳术汤中剂量组和茴香枳术汤高剂量组积气积液消失

肠管恢复正常

气液平面消失

肠梗阻缓解。结论:茴香枳术汤具有良好的治疗粘连性肠梗阻的作用。

Abstract

Objective:To observe the effects of Huixiang Zhizhu soup（HX-S） on abdominal verticalposition plain film radiography in rats with adhesive intestinal obstruction

and provide experimental evidence for the realitionship of abdominal morphological features change with the adhesive intestinal obstruction of HX-S.Method: The Wister rat model of adhesive intestinal obstruction.One hundred and eight rats were randomLy divided into the normal group

model group

Dachengqi soup（DS）group

HX-S low dosage（HX-SL）group

HX-S middle dosage（HX-SM）group and HX-S high dosage（HX-SH）group.Succeed in the model

each group were given medicine.The rats were narcotized after three days

five days and seven days adopt to film abdominal verticalposition X plain

with 6 rats in each subgroup.Observe the change of adhesive intestinal obstruction.Result: Compared with those in normal group

there are some pneumatosis and hydrops

intestinal dilatation

gas and liquid plane obxiously in model group;Compared with those in model group

the level of pneumatosis and hydrops decreased obviously

intestinal recovery

pneumatosis and hydrops disappeared in DS group

HX-SL group

HX-SM group and HX-SH group

intestinal obstruction remission.Conclusion:HX-S has good action effect in rats with adhesive intestinal obstruction.

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Related Author

Wang Zi-li

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LIU Yuan-jie

SHENG Li

WANG Dong-hong

TANG Xiao-yong

LI Liang2

Wang Zi-li1

Related Institution

Department of Clinical Laboratory,Gansu Hospital of Traditional Chinese Medicine

甘肃中医学院

兰州军区兰州总医院医务科

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