Effects of Longyanshen Flavonoids on Epicardial Electrogram and Myocardial Enzymes in Acute Myocardial Ischemic Dogs

ZHAO Hong1; YANG Yu2; WANG Jing-xiang1; LU Wen-wei2

doi:10.13422/j.cnki.syfjx.2011.02.057

您当前的位置：

首页 >

文章列表页 >

Effects of Longyanshen Flavonoids on Epicardial Electrogram and Myocardial Enzymes in Acute Myocardial Ischemic Dogs

更新时间：2024-09-23

- Effects of Longyanshen Flavonoids on Epicardial Electrogram and Myocardial Enzymes in Acute Myocardial Ischemic Dogs
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 2, Pages: 206-208(2011)
- 作者机构：
  
  1. 吉林省柳河医院
  2. 吉林大学白求恩医学院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2011.02.057
  CLC： R285.5
- Published：2011
- 稿件说明：
移动端阅览
[1]赵宏,杨煜,王景祥,吕文伟.龙眼参黄酮对犬急性心肌缺血时心外膜电图及心肌酶的影响[J].中国实验方剂学杂志,2011,17(02):206-208.

ZHAO Hong1, YANG Yu2, WANG Jing-xiang1, et al. Effects of Longyanshen Flavonoids on Epicardial Electrogram and Myocardial Enzymes in Acute Myocardial Ischemic Dogs[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(2): 206-208.
[1]赵宏,杨煜,王景祥,吕文伟.龙眼参黄酮对犬急性心肌缺血时心外膜电图及心肌酶的影响[J].中国实验方剂学杂志,2011,17(02):206-208. DOI： 10.13422/j.cnki.syfjx.2011.02.057.

ZHAO Hong1, YANG Yu2, WANG Jing-xiang1, et al. Effects of Longyanshen Flavonoids on Epicardial Electrogram and Myocardial Enzymes in Acute Myocardial Ischemic Dogs[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(2): 206-208. DOI： 10.13422/j.cnki.syfjx.2011.02.057.

摘要

目的:研究龙眼参黄酮对犬急性心肌缺血时心外膜电图及心肌酶的影响。方法:采用麻醉开胸犬结扎左冠状动脉前降支（LAD）制备急性心肌缺血模型

观察龙眼参黄酮对心外膜电图（EECG）和心肌酶的影响。结果:龙眼参黄酮可减少缺血程度（∑-ST）

降低缺血范围（N-ST）

降低血清中磷酸肌酸激酶（CPK）、乳酸脱氢酶（LDH）的活性

降低血清中游离脂肪酸（FFA）、过氧化脂质（LPO）含量

提高超氧化物歧化酶（SOD）、谷胱甘肽过氧化物（GSH-Px）、一氧化氮（NO）

一氧化氮合酶（NOS）的活性。结论:龙眼参黄酮对实验性心肌缺血犬心肌具有保护作用。

Abstract

Objective:To investigate the effects of Longyanshen flavonoids（LF） on epicardial electrogram（EECG）and myocardial enzymes in acute myocardial ischemic dogs.Method:We adopted anesthetized thoraco-opened dogs to establish the acute myocardial ischemia models by ligation of the left anterior descending branches

the influences of LF were measured by the changes of EECG and myocardial enzymes.Result:It was observed that LF could reduce the severity and area of myocardial ischemia（∑-ST and N-ST）.Moreover

LF not only decreased the content of free fatty acids（FFA） and LPO in serum

as well as the activity of CPK and lactate dehydrogenase（LDH） in serum

but also improved the activity of SOD

glutathione peroxidase（GSH-Px）

nitric oxide（NO）and nitric oxide synthase（NOS）.Conclusion: LF has a protective effect on myocardium in experimental myocardial ischemic dogs.

关键词

Keywords

references

Views

162

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Protective Effect of Baoxin Pills on Experimental Myocardial Ischemia

Wendantang Regulates Energy Metabolism in Treatment of Myocardial Ischemia via SIRT3/PGC-1α Pathway

Effect of Guipitang on ERK1/2 and p38 MAPK in Rats with Myocardial Ischemia

Shexiang Baoxin Pills in Regulation of Angiogenesis in Coronary Heart Disease： A Review

Related Author

ZHAO Hong

YANG Yu

WANG Jing-xiang

LU Wen-wei

Zhang Yu1

Wang Mianzhi2

Huang Qifu2

ZHANG Xinjun

Related Institution

Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine

Nanjing University of Chinese Medicine

Hebei Key Laboratory of Chinese Medicine Research on Cardiocerebrovascular Disease

College of Chemical Technology，Shijiazhuang University

Science and Technology Center，Hebei University of Chinese Medicine

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰