Research on Optimization of Inclusion Technology of Licoflavone β-cyclodextrin by Orthogonal Method

SUN Yun; YAN Xue-hua; GE Liang; SHAN Li-juan

doi:10.13422/j.cnki.syfjx.2011.04.002

您当前的位置：

首页 >

文章列表页 >

Research on Optimization of Inclusion Technology of Licoflavone β-cyclodextrin by Orthogonal Method

更新时间：2024-09-23

- Research on Optimization of Inclusion Technology of Licoflavone β-cyclodextrin by Orthogonal Method
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 4, Pages: 30-32(2011)
- 作者机构：
  
  新疆医科大学中医学院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2011.04.002
  CLC： TQ461
- Published：2011
- 稿件说明：
移动端阅览
[1]孙芸,燕雪花,葛亮,单丽娟.甘草黄酮-β-环糊精包合工艺优化[J].中国实验方剂学杂志,2011,17(04):30-32.

SUN Yun, YAN Xue-hua, GE Liang, et al. Research on Optimization of Inclusion Technology of Licoflavone β-cyclodextrin by Orthogonal Method[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 30-32.
[1]孙芸,燕雪花,葛亮,单丽娟.甘草黄酮-β-环糊精包合工艺优化[J].中国实验方剂学杂志,2011,17(04):30-32. DOI： 10.13422/j.cnki.syfjx.2011.04.002.

SUN Yun, YAN Xue-hua, GE Liang, et al. Research on Optimization of Inclusion Technology of Licoflavone β-cyclodextrin by Orthogonal Method[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 30-32. DOI： 10.13422/j.cnki.syfjx.2011.04.002.

摘要

目的:优化甘草黄酮的β-环糊精包合工艺。方法:采用正交试验对甘草黄酮-β-环糊精包合的主要参数进行考察

以综合评分为指标

筛选最佳工艺

并采用紫外分光光度法和薄层色谱法对包合物进行物相鉴别。结果:甘草黄酮-β-环糊精包合物的最佳工艺为:甘草黄酮与β-环糊精的投料比为1:10

加水量为β-环糊精的10倍

包合温度40℃

搅拌时间1h。结论:饱和水溶液法制备甘草黄酮-β-环糊精

方法可行

操作简单。

Abstract

Objective:To optimize the technology of licorice licoflavone β-cyclodextrin package.Method: Main parameters of licorice flavanone-β-cyclodextrin inclusion were investigated by orthogonal experiment with inclu-sion compound and receive rate as the target to screen out the best technology;the inclusion compound was identified by ultraviolet spectrophotometric method and the thin layer chromatography.Result: The best technique of licofla-vone-β-cyclodextrin inclusion compound was as follows: the batch feeding ratio of licoflavone to β-cyclodextrin was 1∶ 10;the water quantity to be added was 10 times of β-cyclodextrin batch feeding’s;the package temperature was at 40 ℃ and mixed for 1 hour by stirring.Conclusion:The preparation of licoflavone-β-cyclodextrin by saturated aque-ous solution is simple to operate.

关键词

Keywords

references

Views

449

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Research on Optimization of Inclusion Technology of Licoflavone -cyclodextrin by Orthogonal Method

Optimization of Extraction and Inclusion Technology for Volatile Oil from Anti-rheumatism Capsules

Research on Optimum Technology of Preparation Propolis Wrapped with β-cyclodextrin and Its Protective Effect on Radiation Injury in Rats

Related Author

SUN Yun

YAN Xue-hua

GE Liang

SHAN Li-juan

YUE Xiao-hua

DUAN Xiu-jun

SHI Li-xia

WANG Yong-hui

Related Institution

Shanxi University of Traditional Chinese Medicine

Shanxi Renyuantang Pharmaceutical Co.Ltd

College of Life Science and Engineering,Lanzhou University of Technology

Department of Pharmacology,School of Basic Medicine,Capital Medical University

Institute of Basic Theory,China Academy of Traditional Chinese Medicine

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰