WANG Hai-yan1, LIU Ya-ming3, LI Hai-yan1, et al. Effects of Oils in Alpinia officinarum Hance on Serum Motilin,Somatostatin,Substance P,Vasoactive Intestinal Peptide in Gastrelcosis Mice Model[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 105-107.
WANG Hai-yan1, LIU Ya-ming3, LI Hai-yan1, et al. Effects of Oils in Alpinia officinarum Hance on Serum Motilin,Somatostatin,Substance P,Vasoactive Intestinal Peptide in Gastrelcosis Mice Model[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 105-107. DOI: 10.13422/j.cnki.syfjx.2011.04.038.
Effects of Oils in Alpinia officinarum Hance on Serum Motilin,Somatostatin,Substance P,Vasoactive Intestinal Peptide in Gastrelcosis Mice Model
Objective:To observe effects of oils in Alpinia officinarum Hance(OAOH) on serum gastrointes-tinal hormones in gastrelcosis mice model.Method:ICR mice were randomly divided into 7 groups:control group
8 mL.kg-1).The gastrelcosis mice model was induced by reser-pine
which was then given drugs for 6 days.The content of motilin(MOT)
somatostatin(SS)
substance P(SP)
va-soactive in testinal peptide(VIP) in serum were determined by ELISA.Result:Compared with the model group:① All the treatment decreased ulcer index and increased ulcer inhibition rate(P < 0.01).②OAOH
liangfu pills
group racanisodimine obviously decreased MOT
SP in serum(P < 0.01
P < 0.05)
significantly increased SS in serum(P < 0.01
P < 0.05);High dose OAOH increased VIP content in serum(P < 0.01).Conclusion:OAOH treats gas-trelcosis by reducing the content of MOT and SP
Effects of Oils in Hance on Serum Motilin,Somatostatin, Substance P,Vasoactive Intestinal Peptide in Gastrelcosis Mice Model
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Related Author
WANG Hai-yan
LIU Ya-ming
LI Hai-yan
FENG Qian-jin
GUO Jian-you
NIU Xin
Ping-ping BI
Si-qi CHEN
Related Institution
School of Chinese Materia Medica, Guangdong Pharmaceutical University
Beijing University of Chinese Medicine
Hanlin College,Nanjing University of Chinese Medicine
Shaanxi Engineering Technology Research Center of Chinese Herbal Pieces,Shaanxi Qinling Application Development and Engineering Research Center of Chinese Herbal Medicine,Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine(TCM) for TCM Compatibility, Shaanxi University of Chinese Medicine,Xi′an