GENG Xiao-zhao1, XIE Da-sha1, LIU Liang-li2, et al. Influence of Shenqi Feibao on Serum SOD and MDA in Rats with COPD and Qi Deficiency[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 160-162.
GENG Xiao-zhao1, XIE Da-sha1, LIU Liang-li2, et al. Influence of Shenqi Feibao on Serum SOD and MDA in Rats with COPD and Qi Deficiency[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 160-162. DOI: 10.13422/j.cnki.syfjx.2011.04.054.
Influence of Shenqi Feibao on Serum SOD and MDA in Rats with COPD and Qi Deficiency
Objective:To investigate the influence of Shenqi Feibao on rat model of chronic pulmonary dis-ease(COPD)and Qi Deficiency.Moethod:Wistar rat was employed in the study.COPD with Qi deficiency model was estbablished by smoke inhalation combined with papnin administration.Shenqi Feibao treatment was carried out meanwhile as the model was establishing.Two dose groups were designed as 12 and 6 g.kg-1 daily for 60 days.The general conditions
the changes in bronchial and lung and serum SOD
MDA of the rats were observed and deter-mined.Rsult:Shenqi Feibao could improve the systemic and respiratory conditions for the model rats
alleviate the injury in bronchina and lung tissues siginficantly
The high dose of the alleviate the injury in brochinal and lung tis-sues significantly.The high dose of the drug could significantly decrease MDA level compared with that of the model group(P < 0.05).However
the level of SOD in the treatment groups did not change significantly compared with that of the model.Conclusion:Shenqi Feibao has the effect of protectiong airway mucosa
Influence of Shenqi Feibao on Serum SOD and MDA in Rats with COPD and Qi Deficiency
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Related Author
GENG Xiao-zhao
XIE Da-sha
LIU Liang-li
LI Yuan-qing
XIN Jingjing
WANG Tongxing
HAN Ningxin
YANG Yang
Related Institution
Key Laboratory of State Administration of Traditional Chinese Medicine (Cardio-Cerebral Vessel Collateral Disease)
State Key Laboratory for Innovation and Transformation of Luobing Theory
Graduate School, Hebei Medical University
First Affiliated Hospital, Heilongjiang University of Chinese Medicine