ZHANG Kang, HE Yu-xin, WU Li, et al. Study on Optimization of Extraction Technology by Ethanol Refluxing for Zhentong Patch by Orthogonal Design[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(5): 37-39.
ZHANG Kang, HE Yu-xin, WU Li, et al. Study on Optimization of Extraction Technology by Ethanol Refluxing for Zhentong Patch by Orthogonal Design[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(5): 37-39. DOI: 10.13422/j.cnki.syfjx.2011.05.040.
Study on Optimization of Extraction Technology by Ethanol Refluxing for Zhentong Patch by Orthogonal Design
摘要
目的:优选镇痛贴膏的乙醇回流提取工艺。方法:以乙醇体积分数
乙醇用量
提取时间
提取次数为考察因素
用L9(34)正交试验表安排正交试验
以姜黄素转移率
瑞香素转移率
以及干膏收率为考察指标
采用综合加权评分法进行数据分析
优选工艺条件。结果:最佳提取工艺为:药材加70%乙醇10倍量
加热回流2 h
提取2次。结论:该提取工艺客观可行
稳定合理
可为工业化生产提供理论依据。
Abstract
Objective:To optimize the technological condition of ethanol refluxing for Zhentong patch.Method:L9(34) table of orthogonal test was used to optimize the extraction process with alcohol concentration
alco-hol quantity
extraction time and extraction number as the investigate factors
the content of curcumin and daphnetin
dried cream yield as the indexes
to analyze the data by Comprehensive Evaluation of Multiple marks.Result:the best extraction process was as follows:ten times 70% alcohol
to reflux for 2 hour and extracted for 2 times.Conclusion:This extraction process is stable
reasonable and practical
and can provide a theoretical basis for industrial production.