LIU Jian-qun, PAN Jing-hang, ZHANG Rui, et al. Studies on Chemical Constituents of Grewia biloba Ⅱ[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(5): 87-89.
LIU Jian-qun, PAN Jing-hang, ZHANG Rui, et al. Studies on Chemical Constituents of Grewia biloba Ⅱ[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(5): 87-89. DOI: 10.13422/j.cnki.syfjx.2011.05.051.
Studies on Chemical Constituents of Grewia biloba Ⅱ
摘要
目的:研究扁担杆Grewia biloba根皮的化学成分。方法:采用反复硅胶和凝胶柱等色谱分离纯化
根据多种波谱技术鉴定化合物结构。结果:分离鉴定了4个化合物
分别为7-乙氧基槲皮素(1)
1α
3β
23-trihydroxyolean-12-en-28-oic acid(2)
6-C-glucosyl-quercetin(3)
6-C-glucosyl-3
3′
4′
5
7-pentahydroxyflavanone(4)。结论:化合物1为新的天然产物
其余化合物均为首次从该属植物中分离得到。
Abstract
Objective:To investigate the chemical constituents of Grewia biloba.Method:Individual con-stituents
isolated and repeatedly purified on silica gel and Sephadex LH-20 column chromatography
were identified by physicochemical constants and structurally elucidated by spectral methods.Result:Four compounds were isolated and identified as:3′
4′
5
7-tetrahydroxy-7-ethoxyflavone(1)
1α
3β
23-trihydroxyolean-12-en-28-oic acid(2)
6-C-glucosyl-quercetin(3)
6-C-glucosyl-3
3′
4′
5
7-pentahydroxyflavanone(4).Conclusion:Compound 1 is a new natural product
others are isolated from the genus Grewia for the first time.
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Related Author
LIU Jian-qun
PAN Jing-hang
ZHANG Rui
SHU Ji-cheng
LIU Hong-ning
ZHANG Sitong
HU Xianrun
LIU Wenkang
Related Institution
Key Laboratory for Standardization of Chinese Medicines,Ministry of Education, Shanghai Key Laboratory for Compound Chinese Medicines,Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine
Arura Tibetan Medicine Co.Ltd.
Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences
School of TCM,Guangdong Pharmaceutical University
Key Laboratory of Basic and Applied Research of Northern Medicine,Ministry of Education,Heilongjiang Key Laboratory of Pharmacodynamic Material Basis of Traditional Chinese Medicine (TCM) and Natural Medicine,Heilongjiang University of Chinese Medicine