ZHU Min1, DUAN Jin-ao1, TANG Yu-ping1, et al. Inhibition of Contraction of Isolated Mouse Uterine by Siwu Decoction and It’s Composite Drugs[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(5): 149-152.
ZHU Min1, DUAN Jin-ao1, TANG Yu-ping1, et al. Inhibition of Contraction of Isolated Mouse Uterine by Siwu Decoction and It’s Composite Drugs[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(5): 149-152. DOI: 10.13422/j.cnki.syfjx.2011.05.068.
Inhibition of Contraction of Isolated Mouse Uterine by Siwu Decoction and It’s Composite Drugs
Objective:To study the effects of Siwu decoction and its composite drugs on isolated mouse uter-ine contraction in vitro.Methods:The model of isolated mouse uterus contraction was adopted and the inhibition rates of mean contraction force
constriction amplitude
constriction frequency were calculated to evaluated the influ-ence of Siwu decoction and its composite drugs.Result:Siwu decoction and its composite drug-pairs and drugs had certain pharmacological effect on the isolated mouse uterine contraction in vitro
by suppressing the mean contraction force
constriction amplitude and constriction frequency.Conclusion:Angelicae Sinensis Radix and Paeoniae Radix Alba may be the most significant drugs to the model of isolated mouse uterine contraction.The two drugs had syner-getic effect with each other on this activity;Rehmanniae Radix Praeparata and Angelicae Sinensis Radix also had synergetic effect with each other on the activity of suppressing the constriction of isolated mouse uterine;This study provides a reliable reference for the follow-up study.
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Related Author
ZHU Min
DUAN Jin-ao
TANG Yu-ping
HUA Yong-qing
CHEN Fang
SU Shu-lan
QIAN Da-wei
Man-xue YIN
Related Institution
School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine
The Second Clinical Medical College,Guangzhou University of Chinese Medicine
Guangdong Provincial Hospital of Chinese Medicine
Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules in Enterprises,Guangdong Efong Pharmaceutical Co. Ltd.
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