Technological Conditions for Extracting EUP by Uniform Experiment Design

QI Xiao-yuan1; ZHOU Cheng-yan2

doi:10.13422/j.cnki.syfjx.2011.13.035

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Technological Conditions for Extracting EUP by Uniform Experiment Design

更新时间：2024-09-23

- Technological Conditions for Extracting EUP by Uniform Experiment Design
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 13, Pages: 56-59(2011)
- 作者机构：
  
  1. 河北联合大学附属医院检验科
  2. 河北联合大学药学院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2011.13.035
  CLC： R284.1
- Published：2011
- 稿件说明：
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[1]戚晓渊,周程艳.杜仲多糖的均匀设计法提取工艺分析[J].中国实验方剂学杂志,2011,17(13):56-59.

QI Xiao-yuan1, ZHOU Cheng-yan2. Technological Conditions for Extracting EUP by Uniform Experiment Design[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(13): 56-59.
[1]戚晓渊,周程艳.杜仲多糖的均匀设计法提取工艺分析[J].中国实验方剂学杂志,2011,17(13):56-59. DOI： 10.13422/j.cnki.syfjx.2011.13.035.

QI Xiao-yuan1, ZHOU Cheng-yan2. Technological Conditions for Extracting EUP by Uniform Experiment Design[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(13): 56-59. DOI： 10.13422/j.cnki.syfjx.2011.13.035.

摘要

目的:明确杜仲皮中的多糖的提取方法和含量

为杜仲的进一步开发利用提供科学依据。方法:用均匀设计U6（64）表安排杜仲多糖的多因素多水平提取实验

确定杜仲多糖提取的数学模型

得出杜仲多糖率与各因素之间的回归关系

并推算最佳工艺条件。结果:杜仲多糖提取的最佳工艺条件为:杜仲皮粉末质量（g）与加入的水体积（mL）的配比（固液比）=1∶5

温度100℃

提取时间7 h

多糖的最大得率为8.231%。结论:用U6（64）法得到的模型方程

可在设立的因素水平范围内给出杜仲多糖得率极大值

进而探讨各因素对杜仲多糖得率的影响机制。

Abstract

Objective:To clear total polysaccharide content of Eucommia ulmoides Oliver

so as to provide evidence for the future explotion and development of Eucommia ulmoides.Method:The experiment for extracting EUP with multiple factors and multiple levels was designed by the uniform design according to U6（64）and its usage table.The mathematic model for the extraction of EUP was acquired to show the correlation between the EUP and three factors

and the optimal technological conditions were obtained.Result:The optimumextraction technology is:the ratio of solid to liquid being1∶5

extracting temperature being 100 ℃

and extracting time being 7h.Under the optimal condition

the yield rate of the polysaccharide is predicted to be 8.231%.Conclusion:By using U6（64）

the optimal yield rate of EUP can be calculated by the mathematic model within experiment range

and then the factors affecting the extraction of EUP can also be investigated.

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Related Author

QI Xiao-yuan

ZHOU Cheng-yan

Ren-guang WANG

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Zhi-dong QIU

Jing-yao YANG

Xin-shu ZHANG

Ji-qi YANG

Related Institution

College of Pharmacy, Chengdu University of TCM

Key Laboratory of Active Ingredients in Traditional Chinese Medicine(TCM) Co-constructed by Jilin Province and Ministry of Education, Changchun University of Chinese Medicine

Research and Development Centre of New Drugs,Guangxi University of Chinese Medicine

Guangxi Bonger Pharmaceuticals Co.Ltd

Dongguan Hospital of Traditional Chinese Medicine

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