Tumor-inhibitory Effect of Prickly Centipede and Less Thorn Centipede

WANG Shuo1; QIN Wen-hui3

doi:10.13422/j.cnki.syfjx.2011.13.062

您当前的位置：

首页 >

文章列表页 >

Tumor-inhibitory Effect of Prickly Centipede and Less Thorn Centipede

更新时间：2024-09-23

- Tumor-inhibitory Effect of Prickly Centipede and Less Thorn Centipede
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 13, Pages: 156-158(2011)
- 作者机构：
  
  1. 广西药用植物研究所姚新生院士重点实验室
  2. 广西医科大学
  3. 广西中医学院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2011.13.062
  CLC： R285.5
- Published：2011
- 稿件说明：
移动端阅览
[1]王硕,覃文慧.多棘蜈蚣与少棘蜈蚣抗肿瘤作用研究[J].中国实验方剂学杂志,2011,17(13):156-158.

WANG Shuo1, QIN Wen-hui3. Tumor-inhibitory Effect of Prickly Centipede and Less Thorn Centipede[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(13): 156-158.
[1]王硕,覃文慧.多棘蜈蚣与少棘蜈蚣抗肿瘤作用研究[J].中国实验方剂学杂志,2011,17(13):156-158. DOI： 10.13422/j.cnki.syfjx.2011.13.062.

WANG Shuo1, QIN Wen-hui3. Tumor-inhibitory Effect of Prickly Centipede and Less Thorn Centipede[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(13): 156-158. DOI： 10.13422/j.cnki.syfjx.2011.13.062.

摘要

目的:探讨两种蜈蚣的抗肿瘤作用。方法:以MTT法测定两种蜈蚣的含药血清对人肝癌细胞系Bel-7402生长的抑制作用;体内试验将小鼠接种S180实体瘤后检测两种蜈蚣对小鼠S180实体瘤生长的抑制作用。结果:两种蜈蚣均可明显抑制肝癌细胞株Bel-7402的增殖;多棘蜈蚣和少棘蜈蚣0.2

0.4

0.6 g.kg-1对小鼠S180实体型肿瘤均有明显抑制作用（P<0.01）

抑瘤率分别为60.95%

63.68%

69.01%和48.52%

50.18%

50.83%。结论:两种蜈蚣均具有较强的抗肿瘤作用

无论体内和体外试验

多棘蜈蚣均有优于少棘蜈蚣的趋势。

Abstract

Objective:To investigate the effects two kinds of centipede on anti-tumor in vivo.Method:The effect of the two kinds of medicine contained in serum for growth inhibition of human liver cell Bel-7402 was evaluated by MTT.Inhitition of inoculated S180 tumor in mice was used to compare the two kinds of centipede.Result: There were different inhibition for liver cell proliferation of Bel-7402 of the two kinds of centipede;the inhibition rates of S180 tumors in mice were 60.95%

63.68%

69.01% and 48.52%

50.18%

50.83% by the prickly and less thorn of centipede（0.2

0.4

0.6 g·kg-1）.There were obvious inhibition to grow of S180 tumor in mice（P<0.01）.Conclusion: Two kinds of centipede have strong antitumor effect.Prickly centipede shows a tendency of stronger effect than that of the less thorn centipede.

关键词

Keywords

references

Views

397

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Application of Anti-tumor Compatibility Structure of Chinese Medicine

Anti-tumor Mechanism of Traditional Chinese Medicine with Effect of Softening Hardness and Dissipating Mass： A Review

Antioxidant and Anti-tumor Effect and Mechanisms of Andrographis paniculata Polysaccharide on Human Cervical Cancer HeLa Cells

Research Progress in Extraction Technology， Structural Characteristics and Pharmacological Activities of Hippophae rhamnoides Polysaccharides

Related Author

WANG Shuo

QIN Wen-hui

CHEN Lanpin

TAN Feng

WEI Xiaoman

WANG Junyi

LI Liu

WU Mianhua

Related Institution

The Affiliated Hospital of Nanjing University of Chinese Medicine

Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine for Tumor Prevention and Treatment

The First School of Clinical Medicine of Nanjing University of Chinese Medicine

School of Clinical Medicine of Nanjing University of Chinese Medicine

Guang'anmen Hospital， China Academy of Chinese Medical Sciences

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰