WEI Jian-quan, LUO Ying, XUE Qiang, et al. Protective Effect of Kadsura heteroclite on Ethanol-induced Hepatotoxicity in Mice[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(13): 167-169.
WEI Jian-quan, LUO Ying, XUE Qiang, et al. Protective Effect of Kadsura heteroclite on Ethanol-induced Hepatotoxicity in Mice[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(13): 167-169. DOI: 10.13422/j.cnki.syfjx.2011.13.066.
Protective Effect of Kadsura heteroclite on Ethanol-induced Hepatotoxicity in Mice
Objective:To study the protective effect of Kadsura heteroclita(Roxb)Craib(KHC)on ethanol-induced hepatotoxicity in mice.Method: Mice were randomly divided into 5 groups to set up the model of hepatotoxicity by ethanol in mice:the normal
the ethanol model and 3 groups of KHC(33.40
16.70
8.35 g·kg-1).The activities of alanine transaminase(ALT)
aspartate transaminase(AST)
glutathione s-transferase(GST)
superoxide dismutase(SOD)in serum and the contents of malondialdehyde(MDA)
triglyceride(TG)in liver were measured.Result: KHC(33.40
16.70 g·kg-1
qd×7)could reverse the activities of serum ALT
AST
GST
SOD and could decrease the contents of MDA
TG in liver.Conclusion: KHC showed effective protection on ethanol-induced hepatotoxicity.
Evaluation of Anti-osteoporosis Activity and Hepatotoxicity of Xianling Gubao Based on Zebrafish Model
Hepatotoxicity and Anti-osteoporotic Mechanism of Evodiamine
Role of Oxidative Stress in Ulcerative Colitis and Traditional Chinese Medicine Prevention and Treatment: A Review
Acute Toxicity and Hepatotoxicity of Aqueous Extracts of Taxilli Herba from Different Hosts in Zebrafish Model
Related Author
WEI Jian-quan
LUO Ying
XUE Qiang
PAN Yong
ZHENG Zi-min
LI Qiuman
QIAN Yue
ZHU Zixuan
Related Institution
Beijing Key Laboratory of Quality Evaluation of Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine
National Institute for Food and Drug Control
School of Clinical Medicine, Nanjing University
School of Acupuncture-Moxibustion and Tuina,Beijing University of Chinese Medicine
Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medical/Traditional Chinese Medicine(TCM) Processing Technology Inheritance Base of National Administration of TCM, School of Chinese Materia Medica, Beijing University of Chinese Medicine