Preparation Technology of Thymus mongolicus Essential Oil-β-cyclodextrin Inclusion Compound

LI Qian1; FAN Fang-fang1; LI Yao-dong1

doi:10.13422/j.cnki.syfjx.2011.15.024

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Preparation Technology of Thymus mongolicus Essential Oil-β-cyclodextrin Inclusion Compound

更新时间：2024-09-23

- Preparation Technology of Thymus mongolicus Essential Oil-β-cyclodextrin Inclusion Compound
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 15, Pages: 43-45(2011)
- 作者机构：
  
  1. 新疆维吾尔自治区中医医院
  2. 新疆医科大学附属中医医院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2011.15.024
  CLC： R284
- Published：2011
- 稿件说明：
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[1]李茜,范芳芳,黎耀东.百丹胶囊中异株百里香挥发油包合工艺[J].中国实验方剂学杂志,2011,17(15):43-45.

LI Qian1, FAN Fang-fang1, LI Yao-dong1. Preparation Technology of Thymus mongolicus Essential Oil-β-cyclodextrin Inclusion Compound[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(15): 43-45.
[1]李茜,范芳芳,黎耀东.百丹胶囊中异株百里香挥发油包合工艺[J].中国实验方剂学杂志,2011,17(15):43-45. DOI： 10.13422/j.cnki.syfjx.2011.15.024.

LI Qian1, FAN Fang-fang1, LI Yao-dong1. Preparation Technology of Thymus mongolicus Essential Oil-β-cyclodextrin Inclusion Compound[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(15): 43-45. DOI： 10.13422/j.cnki.syfjx.2011.15.024.

摘要

目的:研究异株百里香挥发油β-环糊精（β-CD）包合的制备工艺。方法:以挥发油利用率用正交设计法对异株百里香挥发油β-CD包合工艺进行选。结果:异株百里香挥发油与β-CD包合物最佳制备工艺是挥发油（mL）∶β-环糊精（g）为1∶6在30℃下包合60 min。结论:挥发油包合前后其化学成分没有明显变化

制备工艺适合挥发油包合物的制备。

Abstract

Objective:To study the preparation technology of Thymus mongolicus essential oil-β-cyclodextrin（β-CD） inclusion compound.Method:It was studied with orthogonal design on the extraction of essential oil of T.mongolicus and β-cyclodextrin inclusion compound.Result:The optimum preparation technology for the inclusion compound of T.mongolicus essential oil-β-CD was using the collid mill to grind instantaneously and inclusion rapidly.The best condition was as follows:essential oils to β-CD were 1:6

the temperature for inclusion was 30 ℃

the inclusion time was 60 min.Conclusion:The method to make essential oil from T.mongolicus can easily prepare and produce β-CD on a large scale.

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Related Author

LI Qian

FAN Fang-fang

LI Yao-dong

ZHANG Hong-guo

ZHANG Ru-xue

JIA Zheng-ping

QIU Jian-guo

LI Mao-xing

Related Institution

College of Pharmacy,Lanzhou University

Clinical Pharmacy Key Discipline of State Administration of Traditional Chinese Medicine,Lanzhou General Hospital,Lanzhou Command,,Lanzhou

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