GAO Shan1, CHEN Zhan-ke1, WANG Shu-mei2, et al. Study on Molding Technology of Zhuanshu Grannles[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(15): 46-48.
GAO Shan1, CHEN Zhan-ke1, WANG Shu-mei2, et al. Study on Molding Technology of Zhuanshu Grannles[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(15): 46-48. DOI: 10.13422/j.cnki.syfjx.2011.15.025.
Objective:To optimize the molding technology of Zhuanshu Granules.Method:The effects of different excipients on the formability
hygroscopicity and solubility were investigated.Grading methods of synthesizing multiple guidelines were applied to optimizing excipients and the orthogonal experiment was used to screen out the ratio of the excipients
the concentration and usage of alcohol with formability as index.Result:The optimum composition of prescription consisted of 2 portions of extract powder
1 portion of lactose and 1 portion of dextrin;the best concentration of alcohol was 85% and the usage was 0.12 mL·g-1.The critical relative humidity was 64%.Conclusion:The molding technology is reasonable with good formability
high solubility and is not liable to moisture absorption.