LI Xiao-qian, WANG Xing, LI Ying, et al. Impact of Compatibility of Gastrodiae Rhizoma with Uncariae Ramulus Cum Uncis on Renal Gene Expression of Kidney in SHR Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(15): 131-135.
LI Xiao-qian, WANG Xing, LI Ying, et al. Impact of Compatibility of Gastrodiae Rhizoma with Uncariae Ramulus Cum Uncis on Renal Gene Expression of Kidney in SHR Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(15): 131-135. DOI: 10.13422/j.cnki.syfjx.2011.15.051.
Impact of Compatibility of Gastrodiae Rhizoma with Uncariae Ramulus Cum Uncis on Renal Gene Expression of Kidney in SHR Rats
Objective:To study the impact of compatibility of Gastrodiae Rhizoma with Uncariae Ramulus Cum Uncis on renal gene expression in SHR rats.Method:Four SHR rat groups were established
including Blank
Gastrodia suspension 0.86 g·kg-1 group
Uncariae Remulus Cum Unicis decoction 1.17 g·kg-1 group
Gastrodiae Rhizoma 0.8 g·kg-1 and Uncariae Ramulus Cum Uncis 1.17 g·kg-1 decoction combined.After 10 days of continuous oral administration
mRNA in the kidney of SHR rats was extracted
and then was hybrided with gene chip.After computerized scanning and analyzing
the changes in gene expression were observed.Result:Thirty target genes before and after compatibility of Gastrodiae Rhizoma with Uncariae Ramulus Cum Uncis were selected out.Conclution:After the compatibility of Gastrodiae Rhizoma with Uncariae Ramulus Cum Uncis
the trends of gene expression related with lipid metabolism
Distribution of Isorhynchophyline in Liver and Kidney of SHR Rats before and after Compatiblity of Unicariae Ramulus Cum Uncis with Gastrodiae Rhizoma
Distribution of Gastrodigenin from Gastrodiae Rhizoma in Brain Tissue of SHR Rats Before and After Compatibility with Uncariae Ramulus Cum Uncis
"Compatibility" Relationship of Active Components and Heat-clearing and Blood-cooling Effect of Rehmannia glutinosa Roots
Effects of Compatibility of Ephedrae Herba,Asari Radix et Rhizoma, and Aconiti Lateralis Radix Praeparata on ILC2s-Related Factors in Lung of Allergic Rhinitis Model Mice
Related Author
LI Xiao-qian
WANG Xing
LI Ying
YUAN Lin
ZHANG Wei-guo
WANG Ping
WANG Min-zhi
MI Jia
Related Institution
Henan Provincial Engineering Technology Research Center for Quality Control and Evaluation of Traditional Chinese Medicine, Henan University of Chinese Medicine
College of Agronomy, Henan Agricultural University
Beijing University of Chinese Medicine
School of Traditional Chinese Medicine(TCM),Shanghai University of TCM
Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences