Objective:To investigate the sedation

syngignoscism and anticonvulsant actions of different Fluoritum with different colour.Method:The acute toxicity of Fluoritum with different colour was investigated by mice acute toxicity test.The sedation

syngignoscism and anticonvulsant actionss of the Fluoritum（20 g·kg-1

ig

3 d）were evaluated by testing and observing independent activity

sleep time and convulsion caused by pentrazole in mice.Result:It was not seen the acute toxicity in mice treated by Fluoritum with different colour.Mice treated with Fluoritum reduced the time of independent activities without significant difference.All the Fluoritum with different colour could extend the sleep time of mice with threshold dose of pentobarbital sodium obviously

and showed synergistic effect with pentobarbital sodium.Among them

the 23#

25# showed the obvious differences（P<0.05 or P<0.01）.Fluoritum with different colour did not influenced the time of convulsion of mice significantly.There were no obvious difference and no extension on the elapsed time of convulsion as well.Conclusion:It is not seen the acute toxicity of mice treated with treated Fluoritum with different colour.Fluoritum can reduce the times of independent activities of mice

and extend the sleep time of mice treated with pentobarbital sodium

there for

has synergistic effect with pentobarbital sodium.It has no obvious impact on both the time and the amount of time of convulsion.So

Fluoritum shows sedative action.Fluoritum with different colour shows no significant diffirence.