Objective:To study protective effects of aqueous extract of Cinnamon cassia on the whole cerebral ischemia reperfusion injury in rats.Method: Fifty SD male rats were randomly divided into five groups: normal group

model group

C.cassia group（10

20

40 g·kg-1 as low

moderate and high dose respectively）.The model of the whole cerebral ischemia reperfusion injury was established by four-vessel occlusion（4-VO）.Intragastric administration of C.cassia continued 7 days before modeling and stoped the administration 3 h after the modeling.The activities of MAO and CAT in the brain

heart

liver

kidney tissues were determined by the Ultraviolet Spectrophotometer.Result: Compared with the model groups

the activity of MAO was decreased remarkably（P<0.05 or P<0.01） in all tissues by all doses of C.cassia and the result of the low dose was the best.The activity of CAT in all tissues was enhanced remarkably（P<0.05 or P<0.01） by the high dose

while the activity of CAT in brain and heart was enhanced remarkably（P<0.05 or P<0.01） by the low group and moderate group

without effects in liver and kidney.Conclusion: Aqueous extract of C.cassia had protective effects on the whole cerebral ischemia reperfusion injury in rats

and the mechanism may relate to lipid peroxidation and inhibitory action of MAO.