XU Wei, SUN Wei-feng, LIANG Jing, et al. Effect of Psychological Stress on Gastric Emptying and Gastrointestinal Hormones and the Preventive Effects of Shengjiang Fang in Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(23): 171-173.
XU Wei, SUN Wei-feng, LIANG Jing, et al. Effect of Psychological Stress on Gastric Emptying and Gastrointestinal Hormones and the Preventive Effects of Shengjiang Fang in Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(23): 171-173. DOI: 10.13422/j.cnki.syfjx.2011.23.071.
Effect of Psychological Stress on Gastric Emptying and Gastrointestinal Hormones and the Preventive Effects of Shengjiang Fang in Rats
Objective:To study the effect of psychological stress on gastric emptying and gastrin(GAS)
motilin(MOT) in rats and the preventive effect of Shengjiang Fang.Method:Wistar rats were divided into 4 groups: control group
psychological stress group
psychological stress plus low dose of Shengjiang Fang 5.5 g·kg-1 and high-dose group(11.0 g·kg-1)
respectively.Gastric emptying ratios
GAS and MOT contents were measured.Result:Compared with the control group
the body weight
the gastric emptying ratio and GAS and MOT contents significantly decreased(P<0.01 or P<0.05) in psychological stress group.Compared with the psychological stress group
the body weight and the gastric emptying ratio and GAS and MOT contents both in psychological stress plus low and high-dose of Shengjiang Fang group were all increased(P<0.05).Conclusion:Psychological stress can decrease the gastric emptying rate and the GAS and MOT contents
Shengjiang Fang can antagonize the inhibitory effect of psychological stress on gastric emptying and increase the GAS and MOT contents in rats.
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Related Author
XU Wei
SUN Wei-feng
LIANG Jing
ZHANG Xian-xian
LIU Ling
LI Li
ZHANG Yu-feng
LIU Xin-ai
Related Institution
General Hospital of Tianjin Medical University
National Key Laboratory of Traditional Chinese Medicine(TCM) for Collateral Disease Research and Innovation
Hebei Yiling Medical Research Institute,Key Research Laboratory of National Administration of TCM(Collateral Disease),Key Laboratory of Collateral Diseases of Hebei Province
Hebei Yiling Hospital
First Affiliated Hospital of Henan University of Chinese Medicine