Compatibility Stability of Yuxingcao Injection Mixed with Fifteen Drugs and Three Transfuses

YI Yan1; LIANG Ai-hua1; MA Zhu-feng2; WANG Zhi2; LI Chun-ying1; ZHAO Yong1; GAO Shuang-rong1; XIANG Qin2

doi:10.13422/j.cnki.syfjx.2011.23.082

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Compatibility Stability of Yuxingcao Injection Mixed with Fifteen Drugs and Three Transfuses

更新时间：2024-09-23

- Compatibility Stability of Yuxingcao Injection Mixed with Fifteen Drugs and Three Transfuses
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 23, Pages: 36-39(2011)
- 作者机构：
  
  1. 中国中医科学院中药研究所
  2. 正大青春宝药业有限公司
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2011.23.082
  CLC： R942
- Published：2011
- 稿件说明：
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[1]易艳,梁爱华,马珠凤,王治,李春英,赵雍,高双荣,项琴.鱼腥草注射液与15种药物和3种输液的配伍稳定性研究[J].中国实验方剂学杂志,2011,17(23):36-39.

YI Yan1, LIANG Ai-hua1, MA Zhu-feng2, et al. Compatibility Stability of Yuxingcao Injection Mixed with Fifteen Drugs and Three Transfuses[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(23): 36-39.
[1]易艳,梁爱华,马珠凤,王治,李春英,赵雍,高双荣,项琴.鱼腥草注射液与15种药物和3种输液的配伍稳定性研究[J].中国实验方剂学杂志,2011,17(23):36-39. DOI： 10.13422/j.cnki.syfjx.2011.23.082.

YI Yan1, LIANG Ai-hua1, MA Zhu-feng2, et al. Compatibility Stability of Yuxingcao Injection Mixed with Fifteen Drugs and Three Transfuses[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(23): 36-39. DOI： 10.13422/j.cnki.syfjx.2011.23.082.

摘要

目的:探讨鱼腥草注射液与临床上常用的15种药物和3种输液配伍稳定性

为临床鱼腥草注射液的合理配伍用药提供参考。方法:按照临床配伍方式

将鱼腥草注射液与所选取的15种常用药物和3种输液进行配伍

测定配伍后10 min和2 h的外观、pH、不溶性微粒和鱼腥草素含量的变化。结果:鱼腥草注射液与更昔洛韦和维生素B1配伍后pH均超过了注射剂允许的范围

除了庆大霉素注射液、5%和10%葡萄糖注射液外

鱼腥草注射液与其他注射液配伍含10μm微粒数均超过药典规定

与左氧氟沙星、环丙沙星、庆大霉素、地塞米松和维生素C配伍后

鱼腥草素的含量下降均接近甚至超过10%。结论:鱼腥草注射液与5%和10%葡萄糖注射液无明显配伍禁忌

但应避免与5%葡萄糖盐水和上述15种药物配伍使用。

Abstract

Objective:To determine the compatibility stability of Yuxingcao injection mixed with fifteen drugs and three transfuses.Method:According to clinical compatibility

Yuxingcao injection was mixed with fifteen drugs and three transfuses

and then the appearance

the pH value

the insoluble particles and the content of decanoyl acetaldehyde in the mixed solution were detected.Result: The compatibility of Yuxingcao injection with Ganciclovir and vitamin B1 for injections was obviously changed in PH value;with all injections were significantly increased in insoluble particles except gentamicin injection

5% and 10% glucose injection transfuses

the content of decanoyl acetaldehyde with Levofloxacin

Ciprofloxacin

Gentamycin

Dexamethasone and vitamin C for injections were decreased about ten percent.Conclusion: Yuxingcao injection can be compatible with 5% and 10% glucose injection transfuses

it cannot be compatible with 5% glucose saline injection transfuses and fifteen drugs mentioned above.

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Related Author

YI Yan

LIANG Ai-hua

MA Zhu-feng

WANG Zhi

LI Chun-ying

ZHAO Yong

GAO Shuang-rong

XIANG Qin

Related Institution

College of Agronomy， Henan Agricultural University

Henan Provincial Engineering Technology Research Center for Quality Control and Evaluation of Traditional Chinese Medicine， Henan University of Chinese Medicine

Beijing University of Chinese Medicine

School of Traditional Chinese Medicine（TCM），Shanghai University of TCM

School of Chinese Materia Medica， Beijing University of Chinese Medicine

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