CAI Jing, WANG Wei, HUANG Chen-chen, et al. Optimization of Extraction Process of Flavonoids from Peels of Carya cathayensis by Quadratic General Rotation Unitized Design[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(4): 50-55.
CAI Jing, WANG Wei, HUANG Chen-chen, et al. Optimization of Extraction Process of Flavonoids from Peels of Carya cathayensis by Quadratic General Rotation Unitized Design[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(4): 50-55. DOI: 10.13422/j.cnki.syfjx.2012.04.004.
Optimization of Extraction Process of Flavonoids from Peels of Carya cathayensis by Quadratic General Rotation Unitized Design
Objective:To optimize ultrasonic-assisted extraction technology of flavonoids from peels of Carya cathayensis.Method:Based on peels of C.cathayensis as raw materials
60%ethanol as extraction agent
ultrasonic power 250 W
used quadratic general rotation unitized experimental to design.Based on single factor test
selected ratio of solid-liquid
extraction temperature and extraction time as factors
established regression mathematics model with yield and purity of flavonoids as target.Then got optimization of extraction conditions for flavonoids by analysing variance of test results and optimizing mathematical model.Result:Optimum ultrasonic-assisted extraction technology conditions of flavonoids were as follows:ratio of solid-liquid 1:12
extraction temperature 72 ℃
extraction time 52 min
under these conditions
yield of flavonoids was 2.19%
purity could reach 16.62%.Conclusion:This mathematics model for ultrasonic-assisted extraction of flavonoids from peels of C.cathayensis was feasible.